γ-synuclein Inhibitors
γ-Synuclein inhibitors belong to a class of chemical compounds designed to target and modulate the activity of γ-synuclein, a protein that is primarily found in the central nervous system, including the brain. γ-Synuclein is a member of the synuclein family, which also includes α-synuclein and β-synuclein. These proteins have been of significant interest in the field of neuroscience due to their associations with various neurodegenerative disorders, although γ-synuclein's precise role in these conditions is still under investigation.
The development of γ-synuclein inhibitors stems from the growing body of research suggesting that abnormal aggregation of γ-synuclein may play a role in the pathogenesis of certain neurodegenerative diseases. These inhibitors are designed to interfere with the processes that lead to the aggregation of γ-synuclein, with the ultimate goal of impeding or slowing down the formation of pathological protein deposits. By targeting γ-synuclein, these compounds may offer insights into the underlying mechanisms of neurodegenerative disorders and pave the way for novel strategies. Research into γ-synuclein inhibitors is ongoing, as scientists continue to explore their ability in understanding and mitigating the impact of neurodegenerative diseases on the central nervous system.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is a polyphenol found in grapes and berries. It is known to modulate various signaling pathways and has been shown to reduce the expression of certain proteins involved in neurodegenerative diseases. Its potential to inhibit γ-synuclein expression may be attributed to its antioxidative and anti-inflammatory properties. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is the main active compound in turmeric, possessing anti-inflammatory and antioxidant properties. It has been reported to downregulate the expression of various proteins associated with inflammation and neurodegeneration, suggesting that it might also have the potential to inhibit γ-synuclein expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid found in many fruits and vegetables. It has antioxidant and anti-inflammatory effects, and has been reported to modulate the expression of proteins related to neurodegenerative diseases. Its potential to inhibit γ-synuclein expression could be linked to its ability to modulate cellular signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is a compound found in cruciferous vegetables like broccoli. It is known for its antioxidative properties and ability to induce phase II detoxification enzymes. Sulforaphane may inhibit γ-synuclein expression through its ability to modulate cellular defense mechanisms against oxidative stress. | ||||||
Silybin | 22888-70-6 | sc-202812 sc-202812A sc-202812B sc-202812C | 1 g 5 g 10 g 50 g | $55.00 $114.00 $206.00 $714.00 | 6 | |
Silibinin is a major active constituent of milk thistle. It exhibits antioxidative and anti-inflammatory properties. Research suggests that silibinin can modulate the expression of various proteins and may have the potential to inhibit γ-synuclein expression, contributing to its neuroprotective effects. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine is a central nervous system stimulant found in coffee, tea, and various other beverages. It has been shown to modulate the expression of proteins related to neurodegeneration. Caffeine's potential to inhibit γ-synuclein expression may be linked to its ability to modulate neuronal activity and reduce oxidative stress. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine is an alkaloid found in several plants. It has anti-inflammatory and antioxidative effects. Research suggests that berberine can modulate the expression of proteins related to inflammation and neurodegeneration, and it may have the potential to inhibit γ-synuclein expression. | ||||||
Naringenin | 480-41-1 | sc-219338 | 25 g | $245.00 | 11 | |
Naringenin is a flavonoid found in citrus fruits. It has antioxidant and anti-inflammatory properties. Studies have shown that naringenin can modulate the expression of proteins related to neurodegenerative diseases, suggesting that it might have the potential to inhibit γ-synuclein expression. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3 plays a crucial role in calcium homeostasis and bone metabolism. It also has anti-inflammatory effects and has been shown to modulate the expression of various proteins. Vitamin D3’s potential to inhibit γ-synuclein expression could be linked to its ability to modulate immune responses and reduce inflammation. | ||||||