Date published: 2026-1-7

1-800-457-3801

SCBT Portrait Logo
Seach Input

GABA T-3 Inhibitors

Santa Cruz Biotechnology now offers a broad range of GABA T-3 Inhibitors for use in various applications. GABA T-3 inhibitors are crucial in the study of neurotransmitter regulation and synaptic transmission. Gamma-Aminobutyric Acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, and its levels are tightly regulated by GABA transaminase (GABA-T) enzymes, including GABA T-3. By inhibiting GABA T-3, researchers can explore how increased levels of GABA influence neuronal activity and synaptic plasticity. These inhibitors provide valuable tools for dissecting the biochemical pathways that control GABA metabolism and for understanding the balance between excitation and inhibition in neural circuits. In scientific research, GABA T-3 inhibitors are used to investigate the mechanisms of neurotransmission, the modulation of neuronal excitability, and the interactions between GABAergic and glutamatergic systems. They help to study the role of GABA in various physiological and pathological processes. The availability of GABA T-3 inhibitors supports advanced research into the molecular dynamics of neurotransmitter systems and aids in the development of experimental models for studying neuronal behavior and signaling. View detailed information on our available GABA T-3 Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(S)-SNAP 5114

157604-55-2sc-204257
sc-204257A
5 mg
25 mg
$173.00
$571.00
(0)

(S)-SNAP 5114 acts as a GABA transaminase inhibitor, distinguished by its selective interaction with the enzyme's allosteric site. This compound enhances GABA levels by altering the enzyme's conformation, leading to a decrease in its catalytic efficiency. Its unique stereochemistry allows for specific molecular recognition, promoting a shift in reaction kinetics that favors GABA accumulation. This modulation of enzymatic activity impacts neurotransmitter balance and metabolic regulation.

NNC 05-2090 hydrochloride

184845-43-0sc-204131
sc-204131A
10 mg
50 mg
$235.00
$978.00
(0)

NNC 05-2090 hydrochloride functions as a GABA transaminase inhibitor, characterized by its ability to disrupt the enzyme's substrate binding dynamics. This compound exhibits a unique affinity for the active site, leading to a competitive inhibition that alters the enzyme's catalytic pathway. Its distinct molecular interactions facilitate a reduction in GABA degradation, thereby influencing metabolic pathways and neurotransmitter homeostasis through altered reaction rates.