Date published: 2026-4-24

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G6Pase Inhibitors

Santa Cruz Biotechnology now offers a broad range of G6Pase Inhibitors for use in various applications. G6Pase Inhibitors are specialized compounds that target glucose-6-phosphatase (G6Pase), an enzyme pivotal in the final step of gluconeogenesis and glycogenolysis, where glucose-6-phosphate is hydrolyzed to glucose and inorganic phosphate. This enzyme plays a crucial role in glucose homeostasis by regulating the release of glucose from the liver into the bloodstream. In scientific research, G6Pase Inhibitors are invaluable for studying the regulatory mechanisms of glucose production and release within cells, offering insights into the metabolic pathways that control energy balance. Researchers use these inhibitors to explore the function and regulation of G6Pase in various physiological and biochemical processes, such as metabolic flux and the maintenance of blood glucose levels. G6Pase Inhibitors enable precise modulation of enzyme activity, facilitating detailed studies on the kinetics of glucose metabolism and the impact of altered enzyme function on cellular processes. Additionally, these inhibitors are utilized in structural biology to study the three-dimensional configuration of G6Pase and its interaction sites, providing critical information about its functional domains and regulatory mechanisms. This knowledge is fundamental for advancing our understanding of metabolic control and the integration of glucose metabolism with other cellular pathways. By offering a means to control G6Pase activity, these inhibitors are essential tools for researchers aiming to dissect the complexities of metabolic regulation and glucose homeostasis. View detailed information on our available G6Pase Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

bpV(pic)

148556-27-8sc-221379
sc-221379A
5 mg
25 mg
$88.00
$334.00
11
(1)

bpV(pic) is a potent inhibitor of glucose-6-phosphatase, exhibiting unique interactions with the enzyme's active site. This compound disrupts the enzyme's catalytic mechanism, leading to altered glucose metabolism. Its distinct binding affinity influences reaction kinetics, effectively modulating the hydrolysis of glucose-6-phosphate. Additionally, bpV(pic) engages in specific molecular interactions that can impact cellular energy homeostasis and metabolic pathways, showcasing its role in regulating enzymatic activity.

Thielavin A

71950-66-8sc-202361
500 µg
$806.00
1
(0)

Thielavin A acts as a selective modulator of glucose-6-phosphatase, demonstrating unique binding characteristics that stabilize the enzyme's conformation. This compound influences the enzyme's substrate accessibility, thereby affecting the hydrolysis rate of glucose-6-phosphate. Its distinct molecular interactions can alter the enzyme's catalytic efficiency, leading to significant shifts in metabolic flux. Thielavin A's kinetic profile reveals a nuanced impact on energy regulation within cellular systems.

Thielavin B

71950-67-9sc-202362
500 µg
$307.00
(1)

Thielavin B exhibits a remarkable ability to interact with glucose-6-phosphatase, enhancing its enzymatic activity through specific allosteric modulation. This compound alters the enzyme's affinity for its substrates, resulting in a modified reaction velocity. Its unique structural features facilitate distinct molecular interactions that can influence metabolic pathways, leading to variations in glucose homeostasis. The compound's kinetic behavior underscores its role in fine-tuning energy metabolism at the cellular level.