Date published: 2025-12-10

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G2A Activators

G2A activators constitute a specific category of chemical compounds designed to modulate the activity of the G2A receptor, also known as GPR132. The G2A receptor is a G protein-coupled receptor (GPCR) found on the surface of various cell types, including immune cells and endothelial cells. G2A is recognized for its involvement in the regulation of immune responses, inflammation, and lipid metabolism. This receptor can be activated by a range of ligands, including oxidized lipids and certain protonated molecules, but G2A activators are chemical compounds specifically designed to interact with the receptor and influence its signaling pathways.

G2A activators are engineered to bind to the G2A receptor, eliciting various downstream effects that impact cellular processes. Researchers use these compounds to study the intricate molecular mechanisms associated with G2A receptor activation and its role in immune function, inflammation, and lipid homeostasis. By manipulating G2A activity, scientists can gain valuable insights into the complex interplay between the immune system and metabolic pathways, shedding light on the regulatory networks that govern these physiological processes. G2A activators are instrumental in advancing our understanding of GPCR signaling and its relevance to immune responses and lipid metabolism, contributing to the broader field of cellular and molecular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-α-Lysophosphatidylcholine (from egg yolk)

9008-30-4sc-473611
sc-473611A
sc-473611B
sc-473611C
25 mg
100 mg
500 mg
1 g
$85.00
$235.00
$595.00
$1080.00
1
(0)

L-α-Lysophosphatidylcholine can modulate GPCR activity, potentially influencing G2A expression through cellular signaling pathways related to lipid metabolism.

PGE2

363-24-6sc-201225
sc-201225C
sc-201225A
sc-201225B
1 mg
5 mg
10 mg
50 mg
$56.00
$156.00
$270.00
$665.00
37
(1)

PGE2, an inflammatory mediator, may modulate G2A expression through its action on prostaglandin receptors, which are closely related to GPCR functions.

PAF C-16

74389-68-7sc-201009
sc-201009A
5 mg
25 mg
$128.00
$294.00
10
(1)

Lyso-PAF C-16, a derivative of platelet-activating factor, might affect G2A expression through pathways involved in cell proliferation and inflammation.

Oleic Acid

112-80-1sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$36.00
$102.00
$569.00
$1173.00
10
(1)

Oleic Acid, a monounsaturated fatty acid, may affect G2A expression through mechanisms related to lipid signaling and metabolism.

Arachidonic Acid (20:4, n-6)

506-32-1sc-200770
sc-200770A
sc-200770B
100 mg
1 g
25 g
$90.00
$235.00
$4243.00
9
(1)

Arachidonic Acid, a polyunsaturated fatty acid, can potentially modulate G2A expression through eicosanoid signaling pathways.

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$162.00
$316.00
$559.00
$889.00
$1693.00
7
(1)

D-erythro-Sphingosine-1-phosphate, involved in sphingolipid metabolism, might influence G2A expression by interacting with sphingosine-1-phosphate receptors, affecting various cellular processes.

Oleylethanolamide

111-58-0sc-201400
sc-201400A
10 mg
50 mg
$88.00
$190.00
1
(1)

Oleylethanolamide, an endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, could modulate G2A expression through PPAR-α mediated pathways.

Palmitic Acid

57-10-3sc-203175
sc-203175A
25 g
100 g
$112.00
$280.00
2
(0)

Palmitic Acid, a saturated fatty acid, may affect G2A expression through lipid-related signaling pathways and metabolic regulation.

Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3)

6217-54-5sc-200768
sc-200768A
sc-200768B
sc-200768C
sc-200768D
100 mg
1 g
10 g
50 g
100 g
$92.00
$206.00
$1744.00
$7864.00
$16330.00
11
(1)

DHA, an omega-3 fatty acid, might influence G2A expression through its role in anti-inflammatory pathways and membrane fluidity regulation.

Linoleic Acid

60-33-3sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$33.00
$63.00
$163.00
$275.00
4
(2)

Linoleic Acid, an essential polyunsaturated fatty acid, may modulate G2A expression via pathways associated with lipid metabolism and cellular signaling.