Date published: 2025-10-15

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fetuin-A Inhibitors

Fetuin-A inhibitors are a class of chemical compounds that target and modulate the activity of the protein known as fetuin-A. Fetuin-A, also referred to as alpha-2-HS-glycoprotein (AHSG), is a glycoprotein that is primarily synthesized and secreted by the liver. It plays a crucial role in various physiological processes, including calcium and phosphate homeostasis, as well as inflammation regulation. Fetuin-A inhibitors are designed to interact with and affect the function of fetuin-A within the body. These inhibitors are typically small molecules or compounds that can bind to fetuin-A, either directly or indirectly, thereby altering its activity or downstream signaling pathways. The mechanism of action of fetuin-A inhibitors may involve blocking the binding sites of fetuin-A to its target molecules or receptors, thereby disrupting specific biological processes that rely on fetuin-A's presence or activity. Additionally, some fetuin-A inhibitors may function by modulating the expression or secretion of fetuin-A itself, leading to changes in its concentration within the body. The precise pharmacological properties and mechanisms of fetuin-A inhibitors can vary among different compounds within this class, making it an area of ongoing research and exploration in the field of biochemistry and molecular biology. Understanding how these inhibitors affect fetuin-A function can provide valuable insights into the role of this protein in various physiological processes and may have implications for the development of novel strategies for addressing specific health-related conditions.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Aspirin

50-78-2sc-202471
sc-202471A
5 g
50 g
$20.00
$41.00
4
(1)

Aspirin may inhibit fetuin-A indirectly by reducing inflammation. Fetuin-A levels are associated with inflammation, and aspirin's anti-inflammatory properties can help modulate its expression and activity.

Taurine

107-35-7sc-202354
sc-202354A
25 g
500 g
$47.00
$100.00
1
(1)

Taurine is suggested to inhibit fetuin-A by interfering with its glycation, a process where sugar molecules attach to proteins. This can prevent the formation of advanced glycation end products (AGEs), reducing the impact of fetuin-A on AGE-related processes.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zinc ions can inhibit fetuin-A by binding to it and forming complexes. This can affect its ability to regulate mineralization and may have implications in preventing tissue calcification.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine can downregulate fetuin-A expression and inhibit its secretion from hepatocytes, potentially impacting its systemic levels and associated functions.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin may inhibit fetuin-A through its anti-inflammatory and anti-glycation properties, reducing inflammation and glycation-related processes where fetuin-A is involved.

Heparin

9005-49-6sc-507344
25 mg
$117.00
1
(0)

Heparin, a sulfated glycosaminoglycan, may interact with fetuin-A by binding to its glycosaminoglycan-binding sites, similar to other sulfated glycosaminoglycans, potentially interfering with its functions.

Manganese

7439-96-5sc-250292
100 g
$270.00
(0)

Manganese ions can potentially bind to fetuin-A and disrupt its calcium-binding properties, affecting its role in mineralization regulation.