ferritin heavy chain Activators
The chemical class of Ferritin Heavy Chain Activators encompasses a range of compounds that directly or indirectly influence the activation of ferritin heavy chain, a crucial protein involved in iron storage within cells. These activators play distinct roles in supporting ferritin activity, either by directly contributing to ferritin complex assembly or by modulating cellular iron levels to create a conducive environment for ferritin function. Direct activators, such as Iron(II) sulfate, Ferric Citrate, and Ferric Ammonium Citrate, provide essential ferric ions for the assembly of functional ferritin complexes. These compounds play a direct role in promoting ferritin heavy chain activation by participating in the formation of the ferritin iron core, emphasizing their specific contribution to cellular iron storage processes.
Indirect activators, like Deferoxamine, Lactoferrin, and Apoferritin, influence ferritin heavy chain activity by regulating cellular iron availability. Deferoxamine, as an iron-chelating agent, indirectly supports ferritin function by sequestering iron and ensuring controlled iron levels. Lactoferrin competes for iron binding, contributing to the balanced iron environment necessary for ferritin activity. Apoferritin serves as a structural scaffold, indirectly promoting ferritin activation by providing the framework for iron incorporation. The chemical class collectively underscores the intricate regulation of ferritin heavy chain, emphasizing the importance of balanced iron homeostasis for proper ferritin function. Each activator within this class plays a specific and defined role, either directly participating in ferritin complex assembly or indirectly contributing to the cellular environment conducive to ferritin activity. Understanding the diverse mechanisms of action within this class provides insights into the multifaceted regulation of ferritin heavy chain and its pivotal role in cellular iron management processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Hemin chloride | 16009-13-5 | sc-202646 sc-202646A sc-202646B | 5 g 10 g 25 g | $100.00 $157.00 $320.00 | 9 | |
Hemin, an iron-containing porphyrin, directly activates ferritin heavy chain by providing heme, which serves as a cofactor for ferritin synthesis. Hemin supports the incorporation of iron into the ferritin protein, facilitating its role in iron storage. This compound plays a direct role in ferritin activation by contributing to the formation of functional ferritin complexes. | ||||||
Lactoferrin | 146897-68-9 | sc-394420 sc-394420A sc-394420B sc-394420C | 10 mg 50 mg 100 mg 1 g | $120.00 $400.00 $569.00 $1465.00 | ||
Lactoferrin, an iron-binding glycoprotein, indirectly activates ferritin heavy chain by modulating cellular iron availability. It competes for iron binding, limiting the free iron pool and ensuring a controlled iron environment. By regulating intracellular iron levels, lactoferrin indirectly supports ferritin activity in iron storage processes. | ||||||
Ammonium iron(III) citrate | 1185-57-5 | sc-227256 sc-227256A sc-227256B sc-227256C | 100 g 1 kg 5 kg 10 kg | $49.00 $82.00 $367.00 $683.00 | 2 | |
Ferric citrate directly activates ferritin heavy chain by serving as a source of ferric ions for ferritin complex assembly. Ferritin acts as an iron storage protein, and ferric citrate provides the essential ferric ions necessary for the proper functioning of ferritin in iron sequestration. | ||||||
Iron(III) pyrophosphate tribasic | 10058-44-3 | sc-295192 sc-295192A | 100 g 250 g | $73.00 $148.00 | ||
Ferric pyrophosphate directly activates ferritin heavy chain by providing ferric ions for the formation of ferritin complexes. Ferritin acts as an iron storage protein, and ferric pyrophosphate contributes to the assembly of functional ferritin complexes, facilitating iron sequestration. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $80.00 $200.00 | 5 | |
Ferrous ascorbate directly activates ferritin heavy chain by providing ferrous ions for ferritin complex assembly. Ferritin serves as an iron storage protein, and ferrous ascorbate contributes to the formation of functional ferritin complexes, facilitating iron sequestration. | ||||||
Iron(III) chloride | 7705-08-0 | sc-215192 sc-215192A sc-215192B | 10 g 100 g 500 g | $40.00 $45.00 $85.00 | ||
Ferric chloride directly activates ferritin heavy chain by providing ferric ions for the formation of ferritin complexes. Ferritin acts as an iron storage protein, and ferric chloride contributes to the assembly of functional ferritin complexes, facilitating iron sequestration. | ||||||
Ferrous Sulfate (Iron II Sulfate) Heptahydrate | 7782-63-0 | sc-211505 sc-211505A | 250 g 500 g | $72.00 $107.00 | ||
Ferric sulfate directly activates ferritin heavy chain by providing ferric ions for the formation of ferritin complexes. Ferritin acts as an iron storage protein, and ferric sulfate contributes to the assembly of functional ferritin complexes, facilitating iron sequestration. | ||||||
Iron(III) nitrate nonahydrate | 7782-61-8 | sc-211661 | 100 g | $27.00 | ||
Ferric nitrate directly activates ferritin heavy chain by providing ferric ions for the formation of ferritin complexes. Ferritin acts as an iron storage protein, and ferric nitrate contributes to the assembly of functional ferritin complexes, facilitating iron sequestration. | ||||||