FAM55D Inhibitors

FAM55D Inhibitors include a variety of compounds that interfere with specific signaling pathways implicated in the regulation of FAM55D. Compounds such as PP242, PI-103, and Palomid 529 inhibit mTOR signaling, which is a critical regulator of cell growth and proliferation. If FAM55D's functional activity is linked to mTOR pathways, these inhibitors could result in decreased FAM55D activity by blocking the signals that may promote FAM55D's role in these cellular processes. Other inhibitors target the PI3K/AKT pathway, with ZSTK474, GDC-0941, and PI-103 functioning as PI3K inhibitors, potentially leading to decreased AKT phosphorylation and subsequent reduction in FAM55D activity if it is downstream of PI3K/AKT. Inhibitors such as MK-2206 and AZD5363 specifically target AKT, reducing its activation and possibly leading to decreased FAM55D activity by directly affecting AKT-mediated signaling that may regulate FAM55D. Furthermore, PD0325901 and LY3214996 target the MAPK pathway by inhibiting MEK and ERK, respectively.