Date published: 2026-2-14

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dendrin Inhibitors

Dendrin inhibitors belong to a class of chemical compounds designed to selectively target and modulate the activity of the dendrin protein. Dendrin, also known as ankyrin repeat domain-containing protein 2 (ANKRD2), is a protein that contains multiple ankyrin repeat domains and is primarily expressed in skeletal and cardiac muscles. While the precise function of dendrin is still not fully understood, it is believed to be involved in various cellular processes related to muscle development, sarcomere organization, and gene regulation. Dendrin inhibitors are developed through chemical synthesis and structural optimization techniques, with the primary goal of interacting with specific domains or functional motifs of the dendrin protein to influence its cellular functions.

The design of dendrin inhibitors typically involves creating molecules that can selectively bind to dendrin, potentially disrupting its interactions with other cellular components or interfering with its role in muscle development and gene regulation. By modulating dendrin activity, these inhibitors have the potential to affect processes related to muscle physiology and sarcomere organization, contributing to our understanding of the molecular mechanisms governing muscle development and function. The study of dendrin inhibitors offers valuable insights into the intricate molecular processes underlying muscle biology, providing a deeper understanding of the fundamental processes that govern skeletal and cardiac muscle development and maintenance. This research contributes to our knowledge of basic cell biology and the regulatory networks that control muscle-specific gene expression and muscle structure.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(+)-Bicuculline

485-49-4sc-202498
sc-202498A
50 mg
250 mg
$82.00
$281.00
(1)

A GABA receptor antagonist, bicuculline can modify neuronal excitability, potentially affecting dendrin expression in neurons.

6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-Dione

118876-58-7sc-478080
5 mg
$70.00
1
(0)

An AMPA receptor antagonist, NBQX might influence synaptic transmission and could indirectly affect dendrin expression.

Kainic acid

487-79-6sc-200454
sc-200454A
sc-200454B
sc-200454C
sc-200454D
5 mg
25 mg
100 mg
1 g
5 g
$87.00
$370.00
$1377.00
$7803.00
$24970.00
12
(1)

An agonist for kainate receptors, kainic acid alters neuronal excitability, potentially impacting dendrin expression.

6-Cyano-7-nitroquinoxaline-2,3-dione

115066-14-3sc-505104
10 mg
$208.00
2
(0)

Another AMPA/kainate receptor antagonist, CNQX can affect glutamate-mediated neurotransmission and possibly dendrin expression.

LY 341495

201943-63-7sc-361244
sc-361244A
1 mg
10 mg
$89.00
$223.00
1
(1)

A metabotropic glutamate receptor antagonist, LY341495 can affect neuronal signaling and potentially dendrin expression.

Nimodipine

66085-59-4sc-201464
sc-201464A
100 mg
1 g
$61.00
$307.00
2
(1)

A calcium channel blocker, nimodipine might influence intracellular signaling pathways, potentially affecting dendrin expression.