DCAMKL3 inhibitors refers to a collection of compounds that have been designed and investigated for their ability to inhibit the activity of the protein DCAMKL3 (Doublecortin-like and CAM kinase-like 3), also known as DCLK3. DCAMKL3 is a protein kinase that is implicated in diverse cellular processes, including microtubule dynamics and cell differentiation. Inhibitors developed to target DCAMKL3 are specifically engineered to interact with the catalytic domain of this kinase, thereby perturbing its normal signaling pathways. These inhibitors can have varying chemical structures, reflecting the diverse approaches used by researchers to design molecules that effectively block or modulate the kinase's function.
The specific molecular structures and mechanisms of action of DCAMKL3 inhibitors are likely to differ, as they arise from a range of synthetic strategies and design principles. While some of these inhibitors may exhibit similarities in terms of their interactions with the kinase's active site, it is not accurate to classify them under a single chemical class, as they may incorporate distinct scaffolds and functional groups. The understanding of DCAMKL3 inhibitors and their classification may have evolved, and the most accurate and comprehensive information can be found in the latest research publications and databases.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doramapimod | 285983-48-4 | sc-300502 sc-300502A sc-300502B | 25 mg 50 mg 100 mg | $149.00 $281.00 $459.00 | 2 | |
BIRB 796 is a broad-spectrum kinase inhibitor, and it may have activity against DCAMKL3 among other kinases. | ||||||
GSK 690693 | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1071.00 | 4 | |
This is another broad-spectrum kinase inhibitor, and it might inhibit DCAMKL3 as part of its kinase profile. | ||||||
RO-3306 | 872573-93-8 | sc-358700 sc-358700A sc-358700B | 1 mg 5 mg 25 mg | $66.00 $163.00 $326.00 | 37 | |
RO-3306 has a broader kinase inhibition profile, and it might affect DCAMKL3 activity. | ||||||
SB-505124 | 694433-59-5 | sc-362794 sc-362794A | 10 mg 50 mg | $327.00 $1377.00 | 2 | |
While originally designed as a TGF-beta type I receptor inhibitor, SB-505124 exhibits kinase inhibition properties and may affect DCAMKL3. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Similar to SB-505124, SB-431542 is known as a TGF-beta type I receptor inhibitor, but it also has kinase inhibition properties and could potentially affect DCAMKL3. | ||||||
AZD5363 | 1143532-39-1 | sc-503190 | 5 mg | $309.00 | ||
AZD5363 is a kinase inhibitor that has been explored for its effects on various kinases, and it might exhibit inhibitory activity against DCAMKL3. | ||||||