Date published: 2026-4-1

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DCAMKL3 Inhibitors

DCAMKL3 inhibitors refers to a collection of compounds that have been designed and investigated for their ability to inhibit the activity of the protein DCAMKL3 (Doublecortin-like and CAM kinase-like 3), also known as DCLK3. DCAMKL3 is a protein kinase that is implicated in diverse cellular processes, including microtubule dynamics and cell differentiation. Inhibitors developed to target DCAMKL3 are specifically engineered to interact with the catalytic domain of this kinase, thereby perturbing its normal signaling pathways. These inhibitors can have varying chemical structures, reflecting the diverse approaches used by researchers to design molecules that effectively block or modulate the kinase's function.

The specific molecular structures and mechanisms of action of DCAMKL3 inhibitors are likely to differ, as they arise from a range of synthetic strategies and design principles. While some of these inhibitors may exhibit similarities in terms of their interactions with the kinase's active site, it is not accurate to classify them under a single chemical class, as they may incorporate distinct scaffolds and functional groups. The understanding of DCAMKL3 inhibitors and their classification may have evolved, and the most accurate and comprehensive information can be found in the latest research publications and databases.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Doramapimod

285983-48-4sc-300502
sc-300502A
sc-300502B
25 mg
50 mg
100 mg
$149.00
$281.00
$459.00
2
(1)

BIRB 796 is a broad-spectrum kinase inhibitor, and it may have activity against DCAMKL3 among other kinases.

GSK 690693

937174-76-0sc-363280
sc-363280A
10 mg
50 mg
$255.00
$1071.00
4
(1)

This is another broad-spectrum kinase inhibitor, and it might inhibit DCAMKL3 as part of its kinase profile.

RO-3306

872573-93-8sc-358700
sc-358700A
sc-358700B
1 mg
5 mg
25 mg
$66.00
$163.00
$326.00
37
(1)

RO-3306 has a broader kinase inhibition profile, and it might affect DCAMKL3 activity.

SB-505124

694433-59-5sc-362794
sc-362794A
10 mg
50 mg
$327.00
$1377.00
2
(0)

While originally designed as a TGF-beta type I receptor inhibitor, SB-505124 exhibits kinase inhibition properties and may affect DCAMKL3.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

Similar to SB-505124, SB-431542 is known as a TGF-beta type I receptor inhibitor, but it also has kinase inhibition properties and could potentially affect DCAMKL3.

AZD5363

1143532-39-1sc-503190
5 mg
$309.00
(0)

AZD5363 is a kinase inhibitor that has been explored for its effects on various kinases, and it might exhibit inhibitory activity against DCAMKL3.