Cypt15 Inhibitors represent a group of compounds speculated to exert an indirect influence on the protein Cypt15. This classification emerges from an approach that considers the potential roles of Cypt15 in cellular signaling and the known mechanisms of various chemical compounds in modulating these pathways. The inhibitors listed are not identified through direct interaction studies with Cypt15 but are instead hypothesized based on their capacity to impact cellular mechanisms that Cypt15 might be involved in.
This class includes a diverse array of compounds, each with a distinct mechanism of action. Kinase inhibitors like Rapamycin, PD98059, LY294002, SB203580, and U0126, each targeting different aspects of cell signaling, are included based on their roles in processes such as cell growth, proliferation, differentiation, and response to stress, which could intersect with the pathways involving Cypt15. Compounds like Forskolin, which increases intracellular cAMP, and calcium signaling modulators like W-7 Hydrochloride, BAPTA, and Thapsigargin, are chosen for their potential to alter the cellular signaling environment. These alterations could indirectly affect the activity or regulatory mechanisms of Cypt15. Additionally, the inclusion of Genistein, a tyrosine kinase inhibitor, and Staurosporine, a broad-spectrum protein kinase inhibitor, further expands the scope of targeted biochemical pathways, reflecting the complexity of cellular signaling processes potentially associated with Cypt15.
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