Date published: 2026-3-24

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CtIP Inhibitors

CtIP inhibitors, or inhibitors of the protein known as C-terminal binding protein interacting protein (CtIP), represent a class of chemical compounds that have garnered significant attention in the field of molecular biology and cancer research. CtIP is a crucial protein involved in DNA repair mechanisms, specifically in the process of homologous recombination (HR) and double-strand break repair. HR is a fundamental cellular process that ensures the faithful repair of DNA damage, thereby maintaining genomic stability. CtIP serves as a key factor in this repair pathway by facilitating the generation of single-stranded DNA ends, a crucial step in the HR process. CtIP inhibitors are designed to modulate or disrupt the activity of CtIP, hindering its ability to promote HR and DNA repair. This targeted inhibition of CtIP can have significant implications for understanding the molecular mechanisms underlying DNA repair and genomic instability, which are critical factors in the development and progression of cancer. By interfering with CtIP function, these inhibitors may provide valuable insights into the vulnerabilities of cancer cells and the ability to develop novel strategies to selectively target them. Additionally, CtIP inhibitors can serve as valuable tools in laboratory research to elucidate the intricate pathways and interactions involved in DNA repair processes, advancing our understanding of genome maintenance and repair mechanisms.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has been reported to alter the expression of numerous genes and might decrease CtIP levels by modulating transcription factors and inflammatory pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

As a flavonoid, quercetin can impact various cellular processes, including gene expression, and it might lower CtIP levels through its interactions with signaling pathways.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$45.00
$164.00
$200.00
$402.00
$575.00
$981.00
$2031.00
46
(1)

Genistein, a phytoestrogen, can modulate numerous signaling pathways, potentially leading to a reduction in CtIP expression through its effects on gene transcription and epigenetic modifications.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG, the major catechin in green tea, has been found to influence gene expression and may have the potential to decrease CtIP levels by affecting transcription factors and signaling pathways.

Caffeic acid phenethyl ester

104594-70-9sc-200800
sc-200800A
sc-200800B
20 mg
100 mg
1 g
$71.00
$296.00
$612.00
19
(1)

CAPE has anti-inflammatory properties and can modulate various cellular processes, potentially leading to a downregulation of CtIP expression through transcriptional and post-transcriptional means.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

Ellagic acid has been reported to affect gene expression and cellular pathways, and it might influence CtIP levels by interacting with signaling molecules and transcription factors.

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$39.00
$61.00
$146.00
$312.00
$1032.00
5
(1)

I3C can modulate various cellular processes and has been shown to influence gene expression, potentially leading to a decrease in CtIP levels.

3,3′-Diindolylmethane

1968-05-4sc-204624
sc-204624A
sc-204624B
sc-204624C
sc-204624D
sc-204624E
100 mg
500 mg
5 g
10 g
50 g
1 g
$37.00
$65.00
$89.00
$421.00
$681.00
$66.00
8
(1)

DIM is a compound found in the digestion of indole-3-carbinol and can influence gene expression, potentially leading to reduced CtIP levels.

Ursolic Acid

77-52-1sc-200383
sc-200383A
50 mg
250 mg
$56.00
$180.00
8
(1)

Ursolic acid has anti-inflammatory properties and affects various signaling pathways, potentially resulting in decreased CtIP expression.

Silybin

22888-70-6sc-202812
sc-202812A
sc-202812B
sc-202812C
1 g
5 g
10 g
50 g
$55.00
$114.00
$206.00
$714.00
6
(1)

Silybin has been reported to modulate gene expression and cellular pathways, potentially leading to a decrease in CtIP levels.