Chymostatin Activators
Chymostatin Activators are a set of diverse compounds that indirectly enhance the functional activity of Chymostatin through various signaling mechanisms. Compounds such as Acetylcholine and Epinephrine activate their respective receptors leading to muscle contraction and fight-or-flight responses, with Chymostatin supporting these actions by modulating proteolysis which maintains protein integrity critical for receptor function and signal transduction. Similarly, compounds like Bradykinin and Substance P, known for mediating pain and inflammation, have their signaling prolonged by Chymostatin's inhibition of proteases that would otherwise degrade these mediators, thus enhancing their biological effects. Histamine and Leukotriene B4, pivotal in allergic and inflammatory responses, are also potentiated by Chymostatin as it inhibits the breakdown of signaling molecules, thereby sustaining their action.
In the vascular system, Chymostatin's role is exemplified by its ability to support Thrombin's pro-coagulant activity by inhibiting other serine proteases, thereby fine-tuning the hemostatic balance. The hormone Insulin, essential for glucose metabolism, benefits from Chymostatin's protection against proteolytic degradation, thereby enhancing insulin's efficacy in cellular glucose uptake. Additionally, the influence of neurotransmitters like Serotonin and Oxytocin on mood, cognition, and social behavior is reinforced by Chymostatin through the prevention of proteolytic receptor degradation, ensuring the integrity of these signaling pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bradykinin | 58-82-2 | sc-507311 | 5 mg | $110.00 | ||
Bradykinin activates its receptor to increase vascular permeability and stimulate pain receptors. Chymostatin, as a protease inhibitor, enhances the effects of bradykinin by inhibiting its degradation. | ||||||
Thrombin from human plasma | 9002-04-4 | sc-471713 | 100 U | $235.00 | ||
Thrombin is a serine protease that promotes clot formation. Chymostatin, by inhibiting competing serine proteases, may indirectly enhance the role of thrombin in hemostasis. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates signaling pathways that promote glucose uptake and metabolism. Chymostatin may support insulin action by protecting insulin-degrading enzymes from proteolysis. | ||||||
LTB4 (Leukotriene B4) | 71160-24-2 | sc-201043 | 50 µg | $374.00 | 4 | |
Leukotriene B4 activates leukocytes and induces inflammation. Chymostatin can enhance the inflammatory response by preventing the breakdown of signaling molecules like leukotrienes. | ||||||
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) | 10417-94-4 | sc-200766 sc-200766A | 100 mg 1 g | $104.00 $431.00 | ||
EPA is an omega-3 fatty acid that modulates inflammatory responses. Chymostatin can potentiate the effects of EPA by protecting it from enzymatic degradation. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $530.00 | 3 | |
Serotonin is a neurotransmitter that modulates mood and cognition. Chymostatin can enhance serotonin signaling by inhibiting proteases that degrade serotonin receptors. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine mediates allergic and inflammatory responses. Chymostatin may increase the activity of histamine by inhibiting the proteases involved in its metabolism. | ||||||
Substance P | 33507-63-0 | sc-201169 | 1 mg | $56.00 | ||
Substance P is a neuropeptide that transmits pain signals. Chymostatin may enhance the signaling of substance P by protecting it from degradation by proteases. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine is a hormone and neurotransmitter that mediates the fight-or-flight response. Chymostatin can potentially enhance the physiological effects of epinephrine by stabilizing receptor activity through protease inhibition. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $60.00 $180.00 $337.00 $663.00 $969.00 $1836.00 | 4 | |
Oxytocin is a hormone that regulates social behavior and reproduction. Chymostatin may enhance oxytocin signaling by protecting its receptors from proteolytic degradation. | ||||||