Date published: 2026-2-23

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CHRDL2 Inhibitors

CHRDL2 inhibitors are a and well-defined chemical class characterized by compounds engineered to intricately modulate the intricate functions of the CHRDL2 protein (Chordin-like 2). This protein assumes a multifaceted role in orchestrating an array of vital cellular processes, with prominent involvement in steering embryonic development, orchestrating tissue differentiation, and finely-tuning cellular homeostasis. The inhibitors within this distinct class are meticulously crafted to interact with CHRDL2 in a manner that exerts a controlled impact on its activity or its interactions with other pertinent proteins. Such a calculated intervention serves to exert a discerning influence over the cellular pathways and cascades intricately governed by CHRDL2-mediated signaling. These inhibitors typically emerge in the form of small molecules or peptides, carefully structured to display an inherent affinity for CHRDL2. This unique binding affinity, in turn, equips them to effectively disrupt the interaction between CHRDL2 and its target molecules or impede CHRDL2 from effectively regulating downstream cellular processes. The development and synthesis of CHRDL2 inhibitors necessitate a profound comprehension of the protein's nuanced structure and its multifarious functionalities, alongside a comprehensive grasp of the intricate signaling pathways it underpins. The diligent efforts directed toward CHRDL2 inhibitors endeavor not only to shed light on the intricate tapestry of fundamental cellular mechanisms but also to significantly contribute to the broader domain of molecular biology with far-reaching implications.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BML-275

866405-64-3sc-200689
sc-200689A
5 mg
25 mg
$96.00
$355.00
69
(1)

Dorsomorphin is a small molecule inhibitor that targets BMP signaling pathways, including chrdlIt has been studied for its potential in modulating bone development and other cellular processes.

4-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline

1062368-24-4sc-476297
5 mg
$240.00
(0)

LDN-193189 is a selective inhibitor of BMP type I receptors, including those involved in chrdl2-mediated signaling.

5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline

1432597-26-6sc-476318
5 mg
$380.00
(0)

Similar to LDN-193189, LDN-212854 is a selective BMP type I receptor inhibitor that affects chrdl2-related signaling pathways.

LDN-214117

1627503-67-6sc-507451
5 mg
$165.00
(0)

LDN-214117 is another inhibitor of BMP type I receptors, affecting BMP signaling and chrdl2-related processes.

GW788388

452342-67-5sc-363544
sc-363544A
5 mg
25 mg
$95.00
$384.00
(0)

GW788388 is a selective inhibitor of TGF-β type I receptor kinase, which can modulate chrdl2-mediated effects in certain contexts.