Cerebellin 4 Inhibitors
Cerebellin 4 inhibitors represent a category of chemical compounds that specifically interact with the cerebellin 4 protein or its associated signaling pathways. Cerebellin 4 is part of a family of neuropeptides that play a significant role in the modulation of synaptic functions. These peptides are known to be critical in the fine-tuning of neurotransmitter release and synaptic plasticity, which are essential processes for the proper functioning of the nervous system. The inhibitors of cerebellin 4 are designed to selectively bind to this protein or its receptor, thereby modulating its activity. The precision of this interaction is crucial, as it dictates the specificity and the consequent biochemical outcomes of such inhibition.
In the realm of molecular biology and biochemistry, the study of cerebellin 4 inhibitors encompasses understanding the structural characteristics and the binding affinities of these compounds. This involves examining how inhibitors interact at the molecular level with cerebellin 4 or its receptors, including the dynamics of the binding process and the resulting conformational changes in the target protein. Such studies often employ a range of techniques, including x-ray crystallography, nuclear magnetic resonance (NMR) spectroscopy, and computational modeling to unravel the complex interplay between the inhibitors and the cerebellin 4 protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
6-Cyano-7-nitroquinoxaline-2,3-dione | 115066-14-3 | sc-505104 | 10 mg | $208.00 | 2 | |
AMPA receptor antagonist. Given the role of CBLN4 in synapses, blocking post-synaptic excitatory responses can indirectly influence its functional significance. | ||||||
D(−)-2-Amino-5-phosphonovaleric acid (D-AP5) | 79055-68-8 | sc-200434 | 5 mg | $97.00 | 2 | |
NMDA receptor antagonist. If CBLN4 is associated with glutamatergic transmission, inhibiting NMDA receptors can indirectly modulate its activity. | ||||||
Nimodipine | 66085-59-4 | sc-201464 sc-201464A | 100 mg 1 g | $61.00 $307.00 | 2 | |
Calcium channel blocker often used to prevent calcium overloads in neurons. If CBLN4 function is linked to calcium-dependent processes in the cerebellum, Nimodipine can have an indirect effect. | ||||||
MPEP hydrochloride | 96206-92-7 | sc-279454A sc-279454 | 10 mg 50 mg | $136.00 $520.00 | ||
Selective mGluR5 antagonist. If CBLN4 interacts with or is modulated by metabotropic glutamate receptor signaling, MPEP can indirectly influence its role. | ||||||
(+)-Bicuculline | 485-49-4 | sc-202498 sc-202498A | 50 mg 250 mg | $82.00 $281.00 | ||
GABA-A receptor antagonist. By blocking inhibitory transmission, the synaptic role of CBLN4 in excitatory-inhibitory balance can be indirectly highlighted. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activator of adenylyl cyclase which increases cAMP levels. If CBLN4 activity or expression is modulated by cAMP-dependent signaling, Forskolin can indirectly affect its function. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
Modulator of IP3 receptors and store-operated calcium channels. If CBLN4's function relates to intracellular calcium signaling, 2-APB can indirectly modulate its activity. | ||||||
Riluzole | 1744-22-5 | sc-201081 sc-201081A sc-201081B sc-201081C | 20 mg 100 mg 1 g 25 g | $20.00 $193.00 $213.00 $317.00 | 1 | |
Modulates synaptic neurotransmission and has been known to block glutamate release. If CBLN4 plays a role in glutamatergic synapses, Riluzole can indirectly alter its functional significance. | ||||||
Diethylstilbestrol | 56-53-1 | sc-204720 sc-204720A sc-204720B sc-204720C sc-204720D | 1 g 5 g 25 g 50 g 100 g | $71.00 $287.00 $547.00 $1098.00 $2185.00 | 3 | |
An estrogen that can modulate neurotransmission. If CBLN4 function or expression is influenced by hormonal levels, Diethylstilbestrol can indirectly modulate its activity. | ||||||