Cdc11 Inhibitors

The inhibitors listed above target various cellular processes that are indirectly related to the function of CDC11, especially in the context of cell division, cytokinesis, and septin ring assembly. Latrunculin A and Cytochalasin D, by disrupting actin filaments and inhibiting actin polymerization, respectively, can influence the cytokinesis process in which CDC11 is involved. Nocodazole and Benomyl target microtubule dynamics, which are crucial for cell division, potentially impacting CDC11 function. Compounds like Forskolin and PD98059, which affect signaling pathways, might indirectly influence the regulatory mechanisms involving CDC11.

Myriocin, affecting sphingolipid biosynthesis, and Lovastatin, targeting lipid metabolism, could influence membrane dynamics and indirectly CDC11's function. Rapamycin, as an mTOR inhibitor, affects protein synthesis and cell growth, which are essential for cell division processes involving CDC11. Mitomycin C and Hydroxyurea, which interfere with DNA synthesis and crosslinking, could impact the cell cycle and, consequently, CDC11-related pathways. Staurosporine, being a broad-spectrum kinase inhibitor, might also affect signaling pathways related to CDC11's function in cytokinesis.