CD161 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to suppress the transcription factor NF-κB, which is involved in the expression of various immune response genes. By inhibiting NF-κB, curcumin could specifically reduce the transcription of the CD161 gene, leading to lower protein expression on immune cells. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can activate sirtuin pathways, which are known to contribute to the silencing of gene expression through histone deacetylation. This activity could potentially lead to the decreased expression of CD161 by promoting a closed chromatin conformation at the gene locus. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is known to reduce the production of pro-inflammatory cytokines that may be involved in the upregulation of CD161 expression. By lowering these inflammatory signals, quercetin could contribute to the decreased presence of CD161 on immune cells. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Epigallocatechin gallate, a polyphenol found in green tea, has been shown to inhibit key enzymes in inflammatory pathways. This inhibition could extend to a reduction in CD161 expression if these pathways are involved in its transcriptional regulation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, by binding to estrogen receptors, may exert a repressive effect on certain gene transcriptions, including potentially the CD161 gene. This interaction could lead to a decrease in CD161 mRNA and protein levels. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, as a histone deacetylase inhibitor, can lead to increased acetylation of histones, typically associated with upregulation of gene expression. However, through complex interactions in gene regulatory networks, this could result in the decreased expression of certain genes, such as CD161. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can bind to its receptors and repress the transcription of genes that are not aligned with its differentiation and growth inhibitory effects. This mechanism could hypothetically extend to repressing CD161 expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine can induce DNA demethylation, which often leads to gene activation. However, through indirect effects and changes in the regulatory landscape of the genome, it could contribute to the silencing of genes such as CD161. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate impairs folate metabolism, which is crucial for DNA synthesis and cell replication. Reduced proliferation of CD161-expressing cells could lead to an overall decrease in CD161 expression. | ||||||
hydroxychloroquine | 118-42-3 | sc-507426 | 5 g | $57.00 | 1 | |
Hydroxychloroquine may reduce the overactivation of immune cells, including those expressing CD161. By dampening the immune response, CD161 expression could be consequently decreased, given its role in immune cell function. | ||||||