CD160 activators refer to a class of molecules that have garnered significant attention within the field of immunology and molecular biology. These compounds are primarily associated with modulating the activity of CD160, a cell surface receptor that plays a pivotal role in immune regulation. CD160, also known as BY55 or Natural Killer-1 receptor (NKR), is a glycoprotein receptor expressed on the surface of certain immune cells, particularly natural killer (NK) cells and some subsets of T cells. It is known to be involved in various immunoregulatory processes, although the full extent of its functions is still under investigation. CD160 activators are a group of chemical entities or ligands capable of binding to CD160, thereby influencing its signaling pathways and cellular responses.
These activators can vary in structure and mechanism of action but share a common attribute of interacting with CD160, either directly or indirectly. By engaging with CD160, these compounds can modulate immune cell activities, including cytokine production, cell proliferation, and cytotoxicity, which can ultimately affect the immune response. The research surrounding CD160 activators is ongoing, and the intricacies of how they function in immune regulation continue to be explored.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Directly activates immune cells, including CD160, through PKC activation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Elevates intracellular calcium levels, indirectly contributing to CD160 activation in immune cells. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Influences immune cell activation, including CD160-expressing cells, and their migration, contributing to allergic and inflammatory responses. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $650.00 | 2 | |
Acts as a TLR3 agonist, indirectly influencing CD160-expressing immune responses and antiviral defenses. | ||||||