CCDC138 Inhibitors

Staurosporine and Roscovitine, target a wide range of kinases, potentially impacting numerous signaling cascades that might intersect with CCDC138's function. Compounds like Brefeldin A and Thapsigargin disrupt normal cellular organelle functions, which could alter the environment or processing of proteins like CCDC138. Proteasome inhibitors, such as MG132, and calpain inhibitors, like ALLN, prevent the degradation of proteins, which could indirectly lead to an increase in CCDC138 levels or the stabilization of its structure.

Microtubule-targeting agents, namely Taxol and Nocodazole, affect cell division, and if CCDC138 is involved in this process, these compounds could influence its function. Compounds that modulate the cell cycle, such as Roscovitine and ZM447439, would also be relevant if CCDC138 plays a role in cell cycle regulation. Lithium Chloride and 5-Azacytidine modify signaling and gene expression, respectively, and could indirectly affect the expression or activity of CCDC138. Y-27632 affects cell shape and motility, which are processes that may involve CCDC138 if it functions in cytoskeletal organization.