C3orf34_1500031L02Rik activators are a class of chemical compounds designed to enhance the activity of the protein encoded by the C3orf34 gene in humans, or its ortholog 1500031L02Rik in mice. Unlike inhibitors, which aim to reduce or halt the function of a protein, activators work to increase its action within biological pathways. The mode of action of such activators may involve stabilizing the protein in an active conformation, enhancing its ability to interact with other biomolecules, or increasing its overall expression levels within the cell. The development of these activators requires an in-depth understanding of the protein's structure, the conformational states it undergoes during its functional cycle, and the regulatory mechanisms that control its activity. Chemical activators are often engineered to interact with regions of the protein that are critical for its activation, such as allosteric sites, which are distinct from the active site but can influence the protein's activity when bound by an effector molecule.
Activators of the C3orf34_1500031L02Rik protein are thus important tools in cellular and molecular research. By artificially modulating the activity of the protein, scientists can investigate the downstream effects in various biochemical pathways and gain insights into the protein's role within these processes. The design of such molecules can be complex, requiring iterative cycles of synthesis and testing to identify compounds that are both effective and specific in their action. Advanced techniques in computational chemistry may be used to model interactions between potential activators and the protein at the atomic level, predicting which compounds are most likely to have the desired effect on protein function. Once identified, these activators can be employed in experimental studies, allowing researchers to dissect the biological function of the C3orf34_1500031L02Rik protein, study its interactions with other cellular components, and understand how it contributes to the regulation of cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
A microtubule-stabilizing agent that promotes tubulin polymerization, potentially supporting microtubule structures required for CEP19 function in centrosome and ciliary base. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
A microtubule-destabilizing agent that, at low concentrations, can stimulate microtubule dynamics, indirectly affecting CEP19's role in microtubule anchoring. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
An inhibitor of GSK-3β, which might influence microtubule dynamics and vesicle trafficking, indirectly affecting CEP19's associated pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor that can modulate actin cytoskeleton dynamics, potentially impacting microtubule stability and thus CEP19's function in ciliogenesis. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
A Cdc42 GTPase inhibitor that, through modulating GTPase activity, could have downstream effects on microtubule organization and ciliary function linked to CEP19. | ||||||
ZCL278 | 587841-73-4 | sc-507369 | 10 mg | $115.00 | ||
A Cdc42 GTPase inhibitor that might alter vesicle trafficking and microtubule dynamics, indirectly affecting CEP19's function in ciliogenesis. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $151.00 $609.00 | 75 | |
A Rac1 inhibitor that indirectly impacts actin dynamics and possibly microtubule stability, potentially influencing CEP19's role in cilia formation. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
An inhibitor of actin polymerization that can alter cytoskeletal organization, potentially affecting vesicular processes and ciliary assembly involving CEP19. | ||||||