C330019G07Rik Inhibitors
C330019G07Rik, a protein with diverse cellular implications, is intricately involved in cell growth, differentiation, and apoptosis. Functionally, it modulates key signaling pathways, including the Ras/MAPK, apoptotic, and Bcr-Abl-associated cascades. The intricate interplay of C330019G07Rik in these pathways suggests its role as a crucial orchestrator of cellular responses to various extracellular stimuli. Inhibition of C330019G07Rik is achieved through a spectrum of indirect mechanisms involving key signaling pathways. Imatinib, Nilotinib, and Dasatinib, targeting Bcr-Abl and Src kinases, disrupt the downstream signaling pathways connected to C330019G07Rik, influencing the Ras/MAPK cascade. Selumetinib, a MEK1/2 inhibitor, modulates the Ras/Raf/MEK/ERK pathway, indirectly affecting C330019G07Rik by altering the signaling dynamics. The proteasome inhibitor Bortezomib impacts C330019G07Rik by influencing protein degradation, affecting the stability of proteins involved in pathways linked to C330019G07Rik.
ABT-199, a Bcl-2 inhibitor, indirectly inhibits C330019G07Rik by disrupting the apoptotic pathway, where C330019G07Rik plays a role. The Bcr-Abl kinase inhibitor, Imatinib, further contributes to the indirect inhibition of C330019G07Rik by interfering with the downstream signaling of Bcr-Abl, a pathway interconnected with Ras/MAPK. Collectively, these inhibitors offer valuable insights into the intricate regulatory network governed by C330019G07Rik in cellular processes, paving the way for further investigations into its precise molecular functions and potential implications.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $26.00 $119.00 $213.00 | 27 | |
Imatinib is a tyrosine kinase inhibitor targeting Bcr-Abl and c-Kit. It indirectly influences C330019G07Rik by inhibiting the downstream signaling of Bcr-Abl, which is connected to the Ras/MAPK pathway. The disruption of this cascade impacts the function of C330019G07Rik. | ||||||
Selumetinib | 606143-52-6 | sc-364613 sc-364613A sc-364613B sc-364613C sc-364613D | 5 mg 10 mg 100 mg 500 mg 1 g | $29.00 $82.00 $420.00 $1897.00 $3021.00 | 5 | |
Selumetinib is a MEK1/2 inhibitor, disrupting the Ras/Raf/MEK/ERK pathway. C330019G07Rik interacts with components of this pathway, and Selumetinib indirectly inhibits C330019G07Rik by altering the signaling dynamics. The modulation results in an indirect inhibition of C330019G07Rik. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib is a proteasome inhibitor affecting protein degradation. Indirectly, it influences C330019G07Rik by altering the stability of proteins involved in signaling pathways connected to C330019G07Rik. The disruption of protein homeostasis impacts the function of C330019G07Rik. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib is a dual Bcr-Abl/Src kinase inhibitor. Through inhibition of Src kinase, it influences downstream signaling pathways, including Ras/MAPK. This indirect modulation impacts C330019G07Rik, which is connected to the Ras/MAPK pathway, resulting in altered dynamics of C330019G07Rik. | ||||||
ABT-199 | 1257044-40-8 | sc-472284 sc-472284A sc-472284B sc-472284C sc-472284D | 1 mg 5 mg 10 mg 100 mg 3 g | $118.00 $337.00 $520.00 $832.00 $1632.00 | 10 | |
ABT-199 is a Bcl-2 inhibitor, affecting apoptosis regulation. It indirectly influences C330019G07Rik by modulating the apoptotic pathway, where C330019G07Rik has been implicated. The disruption of apoptosis dynamics leads to an indirect inhibition of C330019G07Rik. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $209.00 $413.00 | 9 | |
Nilotinib is a Bcr-Abl kinase inhibitor, influencing downstream signaling pathways. It indirectly modulates C330019G07Rik through the Ras/MAPK pathway, where C330019G07Rik is interconnected. The alteration in this cascade impacts the function of C330019G07Rik. | ||||||