BTBD3 activators are a diverse group of chemical compounds that enhance the functional activity of BTBD3, either directly or indirectly, through specific biochemical pathways or cellular processes that it is directly involved in. Forskolin, Isoprenaline, Epinephrine, Norepinephrine, L-DOPA (Levodopa), and Dibutyryl-cAMP are compounds that increase intracellular cAMP levels, thereby activating the PKA pathway. This pathway leads to the phosphorylation of proteins involved in cellular homeostasis, indirectly enhancing the function of BTBD3. Sodium Nitroprusside, another activator, generates nitric oxide, activating the cGMP pathway, which, similar to the PKA pathway, can lead to the phosphorylation of proteins involved in cellular homeostasis.
Histamine, Bradykinin, Adenosine Triphosphate (ATP), and Acetylcholine are compounds that increase intracellular calcium levels. Calcium, beinga known cofactor for numerous enzymes, can influence protein-protein interactions, thereby enhancing the functional activity of BTBD3. The increase in intracellular calcium levels induced by these activators potentially enhances the functional activity of BTBD3 by modulating calcium-dependent signaling pathways. Lastly, Nifedipine, an L-type calcium channel blocker, alters the calcium-dependent processes, indirectly enhancing the function of BTBD3 by modulating the calcium-dependent pathways it may be involved in.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is an adenylyl cyclase activator that increases intracellular cAMP levels. The increase in cAMP activates the PKA pathway, which phosphorylates and activates numerous proteins. BTBD3, being involved in protein-protein interactions and ubiquitination, can have its function enhanced by phosphorylation events induced by the increased cAMP. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine is a catecholamine that increases intracellular cAMP levels. Increased cAMP levels can activate the PKA pathway, thereby leading to the phosphorylation of proteins involved in cellular homeostasis, including BTBD3. This indirectly enhances the function of BTBD3. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $326.00 $485.00 | 3 | |
Norepinephrine is a catecholamine that increases intracellular cAMP levels, thereby activating the PKA pathway. This pathway leads to the phosphorylation of proteins involved in cellular homeostasis, indirectly enhancing the function of BTBD3. | ||||||
Levodopa | 59-92-7 | sc-205372 sc-205372A | 5 g 25 g | $54.00 $171.00 | 9 | |
L-DOPA is a precursor to catecholamines and can increase intracellular cAMP levels upon its conversion. Increased cAMP levels can enhance the PKA pathway, leading to phosphorylation of proteins involved in cellular homeostasis, indirectly enhancing the function of BTBD3. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP is a cell-permeable cAMP analog. It activates the PKA pathway, leading to the phosphorylation and activation of various proteins. BTBD3, being involved in protein-protein interactions, can have its functional activity enhanced by the increased phosphorylation events. | ||||||
Sodium nitroprusside dihydrate | 13755-38-9 | sc-203395 sc-203395A sc-203395B | 1 g 5 g 100 g | $43.00 $85.00 $158.00 | 7 | |
Sodium Nitroprusside generates nitric oxide, which activates the cGMP pathway. The cGMP pathway can lead to the phosphorylation of proteins involved in cellular homeostasis, indirectly enhancing the function of BTBD3. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $94.00 $283.00 $988.00 | 7 | |
Histamine, via the H1 receptor, increases intracellular calcium levels. Calcium is a known cofactor for numerous enzymes and can influence protein-protein interactions, thereby potentially enhancing the functional activity of BTBD3. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
ATP, when released into the extracellular space, can bind to P2X receptors, leading to an increase in intracellular calcium levels. Increased calcium levels can enhance protein-protein interactions, thereby indirectly enhancing the function of BTBD3. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine is an L-type calcium channel blocker. By reducing intracellular calcium concentrations, it alters the calcium-dependent processes, indirectly enhancing the function of BTBD3 by modulating the calcium-dependent pathways it may be involved in. | ||||||