Blood Group Lewis a Inhibitors represent a specialized chemical class designed to selectively modulate the expression or function of the Lewis a antigen, a blood group antigen that belongs to the Lewis blood group system. Lewis antigens are carbohydrate structures expressed on the surface of red blood cells and other tissues, playing a role in blood group classification and immune responses. The Lewis a antigen is characterized by its unique carbohydrate composition and is involved in various biological processes, including cell adhesion and immune recognition.
Inhibitors targeting Blood Group Lewis a aim to interfere with the biosynthesis or recognition of this antigen, potentially influencing cellular interactions and immunological responses.The molecular mechanism underlying Blood Group Lewis a Inhibitors may involve disrupting the enzymatic processes involved in the synthesis of the Lewis a antigen or interfering with its binding to specific receptors. By selectively modulating the expression or function of the Lewis a antigen, inhibitors in this chemical class offer researchers a valuable tool to investigate the roles of blood group antigens in cellular adhesion and immune-related processes. The study of Blood Group Lewis a Inhibitors contributes to a deeper understanding of the intricate relationships between blood group antigens and immune responses, shedding light on the complex mechanisms that govern blood compatibility and interactions between cells in various physiological and pathological contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Swainsonine | 72741-87-8 | sc-201362 sc-201362C sc-201362A sc-201362D sc-201362B | 1 mg 2 mg 5 mg 10 mg 25 mg | $138.00 $251.00 $631.00 $815.00 $1832.00 | 6 | |
Swainsonine is an indolizidine alkaloid that inhibits alpha-mannosidases, which are involved in the processing of N-linked glycoproteins. This can potentially affect the glycosylation processes involved in Lewis antigen production. | ||||||
Deoxynojirimycin | 19130-96-2 | sc-201369 sc-201369A | 1 mg 5 mg | $73.00 $145.00 | ||
Deoxynojirimycin is an alpha-glucosidase inhibitor that can affect glycosylation processes. This could potentially have an impact on the production of Lewis antigens. | ||||||
Castanospermine | 79831-76-8 | sc-201358 sc-201358A | 100 mg 500 mg | $184.00 $632.00 | 10 | |
Castanospermine is an indolizidine alkaloid that inhibits glucosidases involved in N-linked glycoprotein processing. This could potentially affect the glycosylation processes involved in Lewis antigen production. | ||||||