ATR Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BEZ235 | 915019-65-7 | sc-364429 | 50 mg | $211.00 | 8 | |
BEZ235 acts as an ATR by selectively inhibiting the activity of specific kinases involved in cellular signaling pathways. Its unique structure allows for precise interactions with the ATP-binding sites of these kinases, leading to altered phosphorylation patterns. The compound demonstrates distinct reaction kinetics, with a fast initial binding phase followed by a prolonged engagement, effectively modulating downstream signaling cascades and influencing cellular responses. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
VE-821 is a selective ATR kinase inhibitor that inhibits ATR-mediated phosphorylation, impacting DNA damage repair processes. | ||||||
ATM/ATR Kinase Inhibitor Inhibitor | 905973-89-9 | sc-202964 | 5 mg | $106.00 | 8 | |
CGK733 inhibits both ATM and ATR kinases, affecting the cellular response to DNA damage. | ||||||
Ceralasertib | 1352226-88-0 | sc-507439 | 10 mg | $573.00 | ||
AZD6738 is a potent inhibitor of ATR kinase activity, which hinders ATR-dependent signaling and disrupts DNA damage repair. | ||||||
ETP-46464 | 1345675-02-6 | sc-497432 | 10 mg | $550.00 | ||
ETP-46464 is a potent and selective ATR inhibitor that disrupts ATR-mediated DNA damage response pathways. | ||||||
SCH 900776 | 891494-63-6 | sc-364611 sc-364611A | 5 mg 10 mg | $255.00 $338.00 | ||
MK-8776 selectively inhibits CHK1, a downstream target of ATR, and indirectly impacts ATR activity. | ||||||
Diminazene Aceturate | 908-54-3 | sc-205651 sc-205651A | 1 g 5 g | $92.00 $377.00 | 11 | |
BERENIL, though primarily a trypanocidal agent, has shown to inhibit ATR kinase activity. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
KU-55933 is primarily an ATM inhibitor but indirectly affects ATR's function within the DNA damage response pathway. | ||||||
KU 60019 | 925701-46-8 | sc-363284 sc-363284A | 10 mg 50 mg | $248.00 $1035.00 | 1 | |
Like KU-55933, KU-60019 inhibits ATM and can indirectly influence ATR's role in DNA damage repair processes. | ||||||
NU6027 | 220036-08-8 | sc-215591 | 10 mg | $156.00 | 1 | |
NU6027 is a potent inhibitor of CDK2 and ATR, impacting the cell cycle and DNA repair processes. | ||||||