Date published: 2026-5-26

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ATP4 Inhibitors

Santa Cruz Biotechnology now offers a broad range of ATP4 Inhibitors for use in various applications. ATP4 inhibitors target the ATP4 proton pump, also known as the H+/K+ ATPase, which is primarily responsible for the secretion of gastric acid in the stomach. In scientific research, these inhibitors are essential tools for studying the mechanisms of acid regulation and the physiological processes underlying acid secretion. By inhibiting ATP4 activity, researchers can explore the role of this proton pump in maintaining pH balance within the stomach and its broader implications in digestive processes. ATP4 inhibitors are particularly valuable in studies focused on understanding the regulation of acid secretion and the cellular signaling pathways involved in gastric acid production. These inhibitors are also used to investigate the molecular mechanisms by which ATP4 contributes to the homeostasis of the gastrointestinal tract, as well as its role in cellular processes like ion transport and membrane potential maintenance. Additionally, ATP4 inhibitors are employed in research examining the impact of altered proton pump activity on cellular and systemic physiology, providing insights into the function of ion pumps in other tissues and organs. The availability of a diverse range of ATP4 inhibitors allows researchers to design experiments tailored to specific aspects of proton pump function, advancing our understanding of acid-base regulation and its importance in maintaining overall physiological balance. View detailed information on our available ATP4 Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pantoprazole

102625-70-7sc-204830
sc-204830A
100 mg
500 mg
$89.00
$255.00
2
(0)

Pantoprazole acts as an ATP4, showcasing a unique capacity to inhibit the H+/K+ ATPase enzyme, which is pivotal in gastric acid secretion. Its structural conformation allows for specific interactions with the enzyme's active site, leading to a significant alteration in proton transport dynamics. The compound exhibits distinct reaction kinetics, with a notable lag phase before achieving peak inhibition, and its lipophilic nature enhances membrane permeability, influencing cellular signaling pathways.

(R)-Omeprazole Sodium Salt

161796-77-6sc-208250
sc-208250A
sc-208250B
sc-208250C
sc-208250D
sc-208250E
sc-208250F
1 mg
5 mg
10 mg
50 mg
100 mg
500 mg
1 g
$250.00
$950.00
$1740.00
$7000.00
$11000.00
$30000.00
$39500.00
1
(1)

(R)-Omeprazole Sodium Salt functions as an ATP4, exhibiting a distinctive ability to modulate proton transport mechanisms. Its stereochemistry contributes to selective binding interactions with specific ion channels, influencing cellular pH regulation. The compound demonstrates unique reaction kinetics, characterized by a rapid onset of action and a prolonged duration of effect. Furthermore, its solubility profile enhances its interaction with membrane proteins, facilitating intricate biochemical pathways.

Rabeprazole Sodium Salt

117976-90-6sc-208255
10 mg
$130.00
(1)

Rabeprazole Sodium Salt functions as an ATP4, demonstrating a selective affinity for the H+/K+ ATPase enzyme, crucial for gastric acid regulation. Its unique molecular structure facilitates strong binding interactions with the enzyme, effectively disrupting proton exchange mechanisms. The compound exhibits rapid onset kinetics, allowing for swift modulation of acid secretion. Additionally, its amphipathic characteristics enhance its solubility in biological membranes, impacting cellular homeostasis and ion transport.