The category of chemicals described as ACTRT2 Inhibitors are compounds whose actions can influence the activity of the human ACTRT2 protein, an actin-related protein. These inhibitors are often chemicals that have known effects on the dynamics and processes associated with actin proteins. ACTRT2, as part of the actin family, is thought to play roles in similar cellular processes, hence the inference that these chemicals can also affect its functioning.
ACTRT2 Inhibitors can work by modulating the actin dynamics in the cell. Some of these chemicals exert their influence by binding to actin monomers, preventing their incorporation into filaments and thereby leading to actin depolymerization. Others bind to the ends of actin filaments, blocking the addition and loss of actin monomers, thus disrupting the balance between polymerization and depolymerization that maintains actin dynamics. There are also compounds that stabilize actin filaments, preventing their disassembly and thereby affecting actin turnover. These diverse mechanisms of action allow for a broad range of influences on the activity and function of ACTRT2. By affecting the processes involving actin, these inhibitors can indirectly influence the function of ACTRT2. As such, these compounds do not directly target ACTRT2, but rather the larger cellular processes in which ACTRT2 and other actin proteins are involved. This distinction is important because it means the effects of these inhibitors are not limited to ACTRT2 but extend to the many proteins involved in actin dynamics. Therefore, the influence of these inhibitors on ACTRT2 is part of a larger effect on the cell's actin system. Understanding this comprehensive impact is crucial for appreciating the effects and implications of these chemicals.
Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D disrupts actin dynamics by binding to the end of actin filaments and blocking the addition and loss of actin monomers. This could potentially affect ACTRT2 if it's involved in similar processes. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A binds to actin monomers and prevents their incorporation into filaments, leading to actin depolymerization. If ACTRT2 is involved in the formation or regulation of actin filaments, Latrunculin A could potentially influence its function. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $180.00 $299.00 | 59 | |
Jasplakinolide stabilizes actin filaments and prevents their disassembly, affecting actin turnover. If ACTRT2 is involved in these processes, Jasplakinolide could potentially influence its function. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $229.00 | 33 | |
Phalloidin binds and stabilizes actin filaments, preventing their disassembly and thus affecting actin dynamics. If ACTRT2's function is related to these processes, Phalloidin could potentially affect its function. |