Angiotensin Receptor Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Angiotensin Receptor inhibitor | sc-3062 | 0.5 mg/0.1 ml | $95.00 | |||
Angiotensin receptor inhibitors exhibit a unique ability to disrupt the angiotensin II signaling pathway by selectively binding to the angiotensin receptors. Their structural conformation allows for specific interactions with receptor binding sites, leading to altered receptor dynamics. This modulation can influence downstream signaling mechanisms, affecting cellular responses. The inhibitors demonstrate varied affinities and kinetics, which can result in distinct biological effects based on their molecular architecture. | ||||||
ent-Valsartan | 137862-87-4 | sc-391260 | 10 mg | $290.00 | ||
Ent-Valsartan is characterized by its selective antagonism of angiotensin II receptors, engaging in unique molecular interactions that stabilize the receptor in an inactive conformation. This compound exhibits a distinct binding affinity, which influences the kinetics of receptor-ligand interactions. Its stereochemistry plays a crucial role in determining the specificity of these interactions, ultimately affecting the modulation of intracellular signaling pathways and cellular homeostasis. | ||||||
Olmesartan acid | 144689-24-7 | sc-219481 sc-219481A sc-219481B sc-219481C sc-219481D | 10 mg 500 mg 1 g 2 g 5 g | $153.00 $204.00 $326.00 $523.00 $1051.00 | 7 | |
Olmesartan acid functions as a potent angiotensin receptor antagonist, exhibiting a unique ability to disrupt the angiotensin II signaling cascade. Its structural conformation allows for specific hydrogen bonding and hydrophobic interactions with the receptor, enhancing its binding efficacy. The compound's kinetic profile reveals a slow dissociation rate, promoting prolonged receptor blockade. Additionally, its distinct molecular architecture contributes to the modulation of downstream signaling events, influencing vascular tone and fluid balance. | ||||||
N-Trityl Candesartan Cilexetil | 886999-34-4 | sc-391404 | 100 mg | $360.00 | ||
N-Trityl Candesartan Cilexetil acts as a selective angiotensin receptor modulator, characterized by its unique trityl group that enhances lipophilicity and receptor affinity. This compound engages in specific electrostatic interactions with the receptor, facilitating a stable binding conformation. Its reaction kinetics indicate a gradual onset of action, allowing for sustained receptor engagement. The compound's structural features also suggest potential allosteric modulation of receptor activity, impacting intracellular signaling pathways. | ||||||
Telmisartan-d3 | 1189889-44-8 | sc-220197 | 1 mg | $370.00 | 1 | |
Telmisartan-d3 is a deuterated derivative of telmisartan, exhibiting enhanced stability and distinct isotopic labeling that can influence metabolic pathways. Its unique molecular structure allows for specific hydrogen bonding interactions with angiotensin receptors, promoting a high degree of selectivity. The presence of deuterium may alter reaction kinetics, potentially leading to prolonged half-life and modified pharmacokinetics. This compound's isotopic characteristics can also facilitate advanced analytical studies in receptor dynamics. | ||||||
N-Trityl Candesartan | 139481-72-4 | sc-212299 | 10 mg | $240.00 | ||
N-Trityl Candesartan is a modified angiotensin receptor antagonist characterized by its bulky trityl group, which enhances lipophilicity and alters receptor binding dynamics. This structural modification facilitates unique hydrophobic interactions, potentially influencing receptor conformation and signaling pathways. The compound's steric properties may also affect its binding kinetics, leading to distinct dissociation rates and affinities compared to its unmodified counterparts, making it a subject of interest in receptor interaction studies. | ||||||