Date published: 2025-9-16

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 341 to 350 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

6-ethyl-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride

sc-337175
100 mg
$150.00
(0)

6-ethyl-2-(4-isopropoxyphenyl)quinoline-4-carbonyl chloride is a notable acid halide characterized by its distinctive quinoline structure and isopropoxy group. The bulky isopropoxy moiety significantly alters the steric environment around the carbonyl, impacting nucleophilic attack rates. This compound exhibits unique reactivity patterns, including the potential for selective acylation and the formation of stable intermediates, which can influence reaction pathways and kinetics in synthetic applications.

8-chloro-2-(3-chlorophenyl)quinoline-4-carbonyl chloride

sc-337401
100 mg
$150.00
(0)

8-chloro-2-(3-chlorophenyl)quinoline-4-carbonyl chloride is an intriguing acid halide featuring a chlorinated quinoline framework. The presence of the 3-chlorophenyl group enhances electron-withdrawing effects, which can stabilize the carbonyl carbon, making it more susceptible to nucleophilic attack. This compound demonstrates unique reactivity, facilitating acylation reactions with various nucleophiles and potentially leading to diverse synthetic pathways. Its distinct electronic properties may also influence reaction kinetics and selectivity in complex chemical transformations.

2-(3,4-dimethylphenoxy)butanoyl chloride

sc-320630
100 mg
$150.00
(0)

2-(3,4-dimethylphenoxy)butanoyl chloride is a notable acid halide characterized by its unique phenoxy group, which introduces steric hindrance and electron-donating effects. This structure enhances the electrophilicity of the acyl chloride, promoting rapid acylation reactions with nucleophiles. The compound's reactivity is influenced by the spatial arrangement of its substituents, allowing for selective transformations in synthetic chemistry. Its behavior in reactions can lead to diverse products, showcasing its versatility in various chemical environments.

2-(4-chloro-3-methylphenoxy)propanoyl chloride

sc-320705
100 mg
$150.00
(0)

2-(4-chloro-3-methylphenoxy)propanoyl chloride is an intriguing acid halide distinguished by its chlorinated aromatic moiety, which enhances its electrophilic character. The presence of the chloro substituent increases the compound's reactivity towards nucleophiles, facilitating swift acylation processes. Additionally, the steric effects from the phenoxy group can influence reaction pathways, allowing for regioselective transformations and the formation of complex derivatives in synthetic applications.

2-(4-isopropylphenoxy)-2-methylpropanoyl chloride

sc-320865
100 mg
$100.00
(0)

2-(4-isopropylphenoxy)-2-methylpropanoyl chloride is a versatile acid halide characterized by its reactivity with nucleophiles, facilitating acylation reactions. Its unique structure, featuring a bulky isopropyl group, enhances steric hindrance, influencing reaction kinetics and selectivity. This compound readily undergoes hydrolysis, generating corresponding acids, and exhibits distinct solubility properties in organic solvents, making it a valuable intermediate in synthetic chemistry.

2-(4-Chloro-2-methylphenoxy)propionyl chloride

sc-320701
1 g
$745.00
(0)

2-(4-Chloro-2-methylphenoxy)propionyl chloride is a reactive acid halide known for its electrophilic nature, which allows it to readily engage in acylation with various nucleophiles. The presence of the chloro substituent introduces unique electronic effects, enhancing its reactivity while also influencing the stability of intermediates formed during reactions. This compound demonstrates significant solubility in non-polar solvents, facilitating its use in diverse synthetic pathways.

2-[(2-fluorobenzyl)oxy]benzoyl chloride

sc-321147
100 mg
$150.00
(0)

2-[(2-fluorobenzyl)oxy]benzoyl chloride is a highly reactive acid halide characterized by its ability to form stable acyl derivatives through nucleophilic acyl substitution. The fluorobenzyl group imparts unique steric and electronic properties, enhancing its reactivity towards amines and alcohols. This compound exhibits a propensity for rapid reaction kinetics, making it suitable for swift transformations in synthetic chemistry. Its solubility in organic solvents further aids in facilitating diverse reaction conditions.

DABSYL chloride

56512-49-3sc-460805
1 g
$122.00
(0)

DABSYL chloride is a potent acid halide known for its exceptional electrophilic character, which allows it to engage in rapid acylation reactions. The presence of the sulfonyl group enhances its reactivity, promoting efficient interactions with nucleophiles such as alcohols and amines. This compound exhibits a distinctive ability to stabilize reaction intermediates, leading to high yields in synthetic pathways. Its compatibility with various solvents broadens its application in diverse chemical environments.

3-[(2,4-dichlorobenzyl)oxy]benzoyl chloride

sc-335662
100 mg
$150.00
(0)

3-[(2,4-dichlorobenzyl)oxy]benzoyl chloride is a highly reactive acid halide characterized by its strong electrophilic nature, facilitating swift acylation processes. The dichlorobenzyl moiety contributes to its unique steric and electronic properties, enhancing selectivity in nucleophilic attacks. This compound demonstrates notable stability in the presence of moisture, allowing for controlled reactions. Its ability to form stable intermediates can lead to efficient synthetic routes, making it a versatile reagent in organic chemistry.

2-(3-butoxyphenyl)-6-methylquinoline-4-carbonyl chloride

sc-320558
100 mg
$150.00
(0)

2-(3-butoxyphenyl)-6-methylquinoline-4-carbonyl chloride is a potent acid halide known for its distinctive reactivity profile. The butoxyphenyl group imparts unique steric hindrance, influencing the kinetics of acylation reactions. This compound exhibits a propensity for rapid nucleophilic substitution, driven by its electrophilic carbonyl carbon. Its structural features allow for selective interactions with various nucleophiles, enabling the formation of diverse carbonyl derivatives in synthetic pathways.