Date published: 2025-9-16

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 331 to 340 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2-(2-naphthyloxy)butanoyl chloride

sc-320465
100 mg
$150.00
(0)

2-(2-naphthyloxy)butanoyl chloride exhibits unique reactivity as an acid halide due to the presence of the naphthyl group, which enhances steric hindrance and electronic effects. This configuration promotes selective nucleophilic attack, allowing for tailored synthesis of complex molecules. Its reactivity is further characterized by the potential for acylation reactions, leading to the formation of esters and amides, thus expanding its utility in synthetic organic chemistry.

6-bromo-3-chloro-1-benzothiophene-2-carbonyl chloride

sc-337094
100 mg
$200.00
(0)

6-bromo-3-chloro-1-benzothiophene-2-carbonyl chloride stands out as an acid halide due to its unique halogen substituents, which influence its electrophilicity and reactivity. The presence of the benzothiophene moiety introduces distinct steric and electronic properties, facilitating rapid acylation reactions with nucleophiles. This compound's ability to engage in diverse coupling reactions enhances its role in constructing complex carbon frameworks, making it a versatile intermediate in organic synthesis.

4-Ethoxy-3-(3-pyridin-2-yl-ureido)-benzenesulfonyl chloride

sc-323112
1 g
$745.00
(0)

4-Ethoxy-3-(3-pyridin-2-yl-ureido)-benzenesulfonyl chloride exhibits remarkable reactivity as an acid halide, characterized by its sulfonyl chloride functionality that enhances electrophilic attack. The presence of the pyridine ring contributes to unique resonance stabilization, influencing reaction pathways and kinetics. This compound readily participates in nucleophilic acyl substitution, allowing for the formation of diverse amides and sulfonamides, thus serving as a key building block in synthetic chemistry.

2-(4-nitrophenoxy)butanoyl chloride

sc-320926
100 mg
$150.00
(0)

2-(4-nitrophenoxy)butanoyl chloride is a highly reactive acid halide, distinguished by its nitrophenoxy group that enhances electrophilicity through resonance effects. This compound readily engages in nucleophilic acyl substitution reactions, facilitating the formation of various acyl derivatives. Its unique electronic properties promote selective reactivity, allowing for tailored synthesis pathways. The presence of the electron-withdrawing nitro group further modulates reaction kinetics, making it a versatile intermediate in organic synthesis.

4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl chloride

sc-323277
100 mg
$250.00
(0)

4,5,6,7-tetrahydro-1-benzothiophene-3-carbonyl chloride is a potent acid halide characterized by its unique bicyclic structure, which introduces steric hindrance that influences reactivity. This compound exhibits a strong electrophilic nature, enabling rapid nucleophilic attack and acylation reactions. Its distinct thiophene ring contributes to unique electronic interactions, enhancing selectivity in acylation processes. The compound's reactivity profile allows for the efficient formation of diverse carbonyl derivatives, making it a valuable intermediate in synthetic chemistry.

2-(4-chlorophenyl)-6-ethylquinoline-4-carbonyl chloride

sc-320723
100 mg
$150.00
(0)

2-(4-chlorophenyl)-6-ethylquinoline-4-carbonyl chloride is a distinctive acid halide featuring a quinoline backbone that imparts notable electronic properties. The presence of the chlorophenyl group enhances its electrophilicity, facilitating swift nucleophilic attacks. This compound's unique structure promotes selective acylation pathways, allowing for the formation of various derivatives. Its reactivity is further influenced by steric factors, making it a versatile intermediate in organic synthesis.

p-Tolyl-acetyl chloride

35675-44-6sc-331665
1 g
$640.00
(0)

p-Tolyl-acetyl chloride is a notable acid halide characterized by its aromatic tolyl group, which contributes to its electrophilic nature. The compound exhibits rapid reactivity with nucleophiles, driven by the electron-withdrawing effect of the acyl chloride functional group. Its unique steric and electronic properties enable selective acylation reactions, leading to diverse synthetic pathways. Additionally, the compound's stability under certain conditions allows for controlled reaction kinetics, making it a useful intermediate in various organic transformations.

Hex-5-enoyl chloride

36394-07-7sc-337863
sc-337863A
1 g
10 g
$560.00
$4000.00
(0)

Hex-5-enoyl chloride is a distinctive acid halide featuring a conjugated double bond that enhances its reactivity profile. The presence of the unsaturated carbon chain facilitates unique electrophilic interactions, allowing for rapid addition reactions with nucleophiles. Its structure promotes regioselectivity in acylation processes, enabling the formation of diverse products. Furthermore, the compound's ability to undergo polymerization under specific conditions highlights its versatility in synthetic chemistry.

2-(2-chlorophenyl)quinoline-4-carbonyl chloride

sc-320430
100 mg
$150.00
(0)

2-(2-chlorophenyl)quinoline-4-carbonyl chloride is a notable acid halide characterized by its aromatic and heterocyclic components, which contribute to its electrophilic nature. The presence of the chlorophenyl group enhances its reactivity, allowing for selective acylation reactions. This compound exhibits unique steric effects that influence reaction kinetics, promoting specific pathways in nucleophilic substitution. Its ability to form stable intermediates further underscores its utility in complex synthetic transformations.

7-chloro-2-(3-ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride

sc-337313
100 mg
$150.00
(0)

7-chloro-2-(3-ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride is an intriguing acid halide distinguished by its unique quinoline framework and ethoxy substitution. The electron-donating ethoxy group modulates the electrophilicity of the carbonyl, facilitating diverse acylation reactions. Its steric configuration influences the orientation of nucleophiles, leading to regioselective outcomes. Additionally, the compound's ability to engage in intramolecular interactions can stabilize transition states, enhancing reaction efficiency.