Date published: 2025-10-2

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 251 to 260 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3-Phenyl-butyryl chloride

51552-98-8sc-322623
1 g
$745.00
(0)

3-Phenyl-butyryl chloride is a highly reactive acid halide known for its strong electrophilic character, which promotes rapid acylation reactions. The phenyl group enhances its ability to stabilize transition states, influencing reaction kinetics and selectivity during nucleophilic attacks. This compound exhibits distinct solubility properties in various organic solvents, which can affect its reactivity and compatibility in synthetic routes, allowing for the formation of a wide range of derivatives.

5-(chlorosulfonyl)-2,3-dimethoxybenzoic acid

sc-350283
sc-350283A
250 mg
1 g
$197.00
$399.00
(0)

5-(Chlorosulfonyl)-2,3-dimethoxybenzoic acid is a potent acid halide characterized by its unique sulfonyl chloride functionality, which enhances its electrophilicity. This compound facilitates nucleophilic acyl substitution reactions, exhibiting a preference for specific nucleophiles due to steric and electronic effects from the methoxy groups. Its solubility in polar solvents allows for efficient reaction pathways, making it a versatile intermediate in organic synthesis.

4-Isopropylbenzoyl chloride

21900-62-9sc-323164
1 g
$745.00
(0)

4-Isopropylbenzoyl chloride is a distinctive acid halide known for its bulky isopropyl group, which influences its reactivity and steric hindrance. This compound exhibits strong electrophilic behavior, promoting rapid nucleophilic acyl substitution reactions. The presence of the aromatic ring enhances resonance stabilization, affecting reaction kinetics and selectivity. Its solubility in organic solvents facilitates diverse synthetic pathways, making it a key player in various chemical transformations.

N-[4-(chloroacetyl)phenyl]-N-methylmethanesulfonamide

sc-355298
sc-355298A
250 mg
1 g
$197.00
$399.00
(0)

N-[4-(chloroacetyl)phenyl]-N-methylmethanesulfonamide is a notable acid halide characterized by its unique sulfonamide moiety, which enhances its electrophilic nature. The chloroacetyl group introduces a reactive carbonyl, facilitating swift nucleophilic attacks. Its molecular structure allows for specific interactions with nucleophiles, leading to distinct reaction pathways. Additionally, the compound's moderate polarity influences solubility in various solvents, enabling versatile synthetic applications.

2-Chlorophenyl chloroformate

19358-41-9sc-225317
5 g
$55.00
(0)

2-Chlorophenyl chloroformate is a distinctive acid halide known for its reactivity due to the presence of the chloroformate group, which enhances its electrophilic character. This compound readily undergoes nucleophilic acyl substitution, making it a potent acylating agent. Its unique structure allows for selective interactions with amines and alcohols, promoting rapid reaction kinetics. The compound's moderate polarity also affects its solubility, facilitating diverse synthetic routes in organic chemistry.

Nonafluoro-1-butanesulfonyl chloride

2991-84-6sc-255395
sc-255395A
sc-255395B
1 g
5 g
25 g
$98.00
$294.00
$1044.00
(0)

Nonafluoro-1-butanesulfonyl chloride is a highly reactive acid halide characterized by its strong electrophilic nature, attributed to the sulfonyl chloride functional group. This compound exhibits exceptional reactivity with nucleophiles, enabling efficient acylation processes. Its unique fluorinated structure imparts distinct electronic properties, enhancing its interaction with various substrates. The compound's low polarity influences solubility and reactivity, making it a versatile intermediate in synthetic organic chemistry.

2-Benzyloxyethyl chloroformate

56456-19-0sc-229963
5 g
$161.00
(0)

2-Benzyloxyethyl chloroformate is a reactive acid halide known for its ability to facilitate acylation reactions through its electrophilic chloroformate group. The presence of the benzyloxy moiety enhances its stability while also providing a site for nucleophilic attack. This compound exhibits unique reactivity patterns, allowing for selective modifications in complex organic syntheses. Its moderate polarity influences solubility, impacting reaction kinetics and pathways in various chemical environments.

methyl 2-bromo-5-(chlorosulfonyl)benzoate

sc-353783
sc-353783A
250 mg
1 g
$197.00
$399.00
(0)

Methyl 2-bromo-5-(chlorosulfonyl)benzoate is a distinctive acid halide characterized by its electrophilic chlorosulfonyl group, which enhances its reactivity in nucleophilic substitution reactions. The presence of the bromo substituent introduces steric hindrance, influencing the selectivity of reactions. This compound's unique electronic properties facilitate diverse pathways in organic synthesis, while its moderate polarity affects solubility and reactivity in various solvents, shaping its interaction dynamics.

4-Bromomethyl benzoyl bromide

876-07-3sc-252134
5 g
$75.00
(0)

4-Bromomethyl benzoyl bromide is a notable acid halide distinguished by its highly reactive bromomethyl and carbonyl functionalities. The bromine atoms enhance electrophilicity, promoting rapid acylation reactions with nucleophiles. Its unique steric and electronic environment allows for selective transformations, while the compound's polar nature influences its solubility in organic solvents, affecting reaction kinetics and pathways in synthetic applications.

4-Fluoro-2-methylbenzenesulfonyl chloride

7079-48-3sc-232682
1 g
$26.00
(0)

4-Fluoro-2-methylbenzenesulfonyl chloride is a reactive acid halide characterized by its sulfonyl chloride group, which enhances its electrophilic nature. The presence of the fluorine atom introduces unique electronic effects, increasing the compound's reactivity towards nucleophiles. This compound exhibits distinct solvation properties, influencing its interaction with solvents and reaction rates. Its ability to form stable intermediates facilitates diverse synthetic pathways, making it a versatile reagent in organic chemistry.