Date published: 2025-9-29

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 231 to 240 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Chloro-2-nitrobenzenesulfonyl chloride

sc-323455
5 g
$201.00
(0)

5-Chloro-2-nitrobenzenesulfonyl chloride is a notable acid halide characterized by its strong electrophilic nature due to the sulfonyl chloride moiety. This compound exhibits rapid reactivity with amines and alcohols, facilitating the formation of sulfonamides and esters. The nitro group enhances the electrophilicity of the aromatic ring, promoting electrophilic aromatic substitution. Its unique structure allows for selective functionalization, making it a key player in diverse synthetic pathways.

Pentadecafluorooctanoyl chloride

335-64-8sc-228908
5 g
$68.00
(0)

Pentadecafluorooctanoyl chloride is a notable acid halide characterized by its high electronegativity and unique fluorinated carbon chain. This compound exhibits strong reactivity due to the presence of the acyl chloride moiety, facilitating rapid nucleophilic attack. The fluorinated segments impart distinct hydrophobic properties, influencing solubility and interaction with various nucleophiles. Its robust carbon-fluorine bonds contribute to stability, while also enabling selective reactions in diverse synthetic pathways.

10-Camphorsulfonyl chloride

4552-50-5sc-223139
25 g
$116.00
(0)

10-Camphorsulfonyl chloride is a distinctive acid halide known for its bulky camphor-derived structure, which enhances steric hindrance during reactions. This compound exhibits a high degree of electrophilicity due to the sulfonyl chloride functional group, promoting swift nucleophilic substitution. Its unique spatial arrangement influences reaction kinetics, allowing for selective interactions with various nucleophiles. Additionally, the compound's polar nature affects solubility and reactivity in organic synthesis.

Propionyl bromide

598-22-1sc-236482
5 g
$49.00
(0)

Propionyl bromide is a notable acid halide characterized by its reactivity and ability to form acyl derivatives. The presence of the bromine atom enhances its electrophilic nature, facilitating rapid acylation reactions with nucleophiles. Its moderate polarity influences solubility in organic solvents, while the compound's linear structure allows for efficient steric interactions during synthesis. This results in distinct reaction pathways, particularly in the formation of esters and amides.

4-(Chlorosulfonyl)phenyl isocyanate

6752-38-1sc-232268
sc-232268A
1 g
5 g
$113.00
$384.00
(0)

4-(Chlorosulfonyl)phenyl isocyanate is a highly reactive acid halide distinguished by its unique sulfonyl and isocyanate functional groups. The chlorosulfonyl moiety enhances electrophilicity, promoting swift nucleophilic attack and facilitating the formation of diverse derivatives. Its polar nature contributes to solubility in polar organic solvents, while the compound's planar structure allows for effective π-stacking interactions, influencing reaction kinetics and selectivity in synthetic pathways.

Cyclopentanecarbonyl chloride

4524-93-0sc-234476
5 g
$61.00
(0)

Cyclopentanecarbonyl chloride is a versatile acid halide characterized by its cyclic structure, which imparts unique steric effects that influence reactivity. The carbonyl group exhibits strong electrophilic properties, making it susceptible to nucleophilic attack, while the presence of the chloride enhances its reactivity in acylation reactions. Its moderate polarity allows for solubility in various organic solvents, facilitating diverse synthetic routes and enabling selective transformations in organic synthesis.

5-Bromovaleryl chloride

4509-90-4sc-233302
5 g
$38.00
(0)

5-Bromovaleryl chloride is a distinctive acid halide featuring a linear structure that promotes specific steric interactions, enhancing its reactivity profile. The bromine atom introduces unique electronic effects, increasing the electrophilicity of the carbonyl group and facilitating rapid nucleophilic acyl substitution. Its relatively high reactivity allows for efficient coupling reactions, making it a valuable intermediate in various synthetic pathways, while its moderate polarity aids in solubility across organic solvents.

4-methoxy-6-methylbenzene-1,3-disulfonyl dichloride

sc-352488
sc-352488A
1 g
5 g
$266.00
$793.00
(0)

4-Methoxy-6-methylbenzene-1,3-disulfonyl dichloride is a notable acid halide characterized by its dual sulfonyl groups, which significantly enhance its electrophilic nature. The presence of the methoxy and methyl substituents influences steric hindrance, allowing for selective reactivity in nucleophilic acyl substitutions. This compound exhibits unique reaction kinetics, often leading to rapid formation of stable adducts, and its distinct solubility properties facilitate diverse synthetic applications in organic chemistry.

ethyl 4-(chlorosulfonyl)butanoate

sc-353477
sc-353477A
250 mg
1 g
$248.00
$510.00
(0)

Ethyl 4-(chlorosulfonyl)butanoate is an intriguing acid halide that features a chlorosulfonyl group, which imparts strong electrophilic character, making it highly reactive towards nucleophiles. The compound's unique structure promotes specific molecular interactions, enabling selective acylation reactions. Its reactivity is influenced by the butanoate moiety, which can stabilize intermediates, leading to distinct pathways in synthetic transformations. Additionally, its solubility profile allows for effective manipulation in various organic reactions.

3-methanesulfonamido-2,4,6-trimethylbenzene-1-sulfonyl chloride

sc-347011
sc-347011A
250 mg
1 g
$197.00
$399.00
(0)

3-Methanesulfonamido-2,4,6-trimethylbenzene-1-sulfonyl chloride is a distinctive acid halide characterized by its sulfonamide and sulfonyl chloride functionalities, which enhance its electrophilic reactivity. The presence of multiple methyl groups contributes to steric hindrance, influencing reaction kinetics and selectivity in acylation processes. This compound's unique electronic properties facilitate specific interactions with nucleophiles, enabling tailored synthetic pathways and efficient formation of sulfonamide derivatives.