Date published: 2025-12-14

1-800-457-3801

SCBT Portrait Logo
Seach Input

3beta-HSD Inhibitors

Santa Cruz Biotechnology now offers a broad range of 3beta-HSD Inhibitors for use in various applications. 3beta-HSD inhibitors are specialized compounds that target the enzyme 3β-hydroxysteroid dehydrogenase, which is pivotal in the biosynthesis of all classes of hormonal steroids, including glucocorticoids, mineralocorticoids, and androgens. This enzyme catalyzes the conversion of Δ5-steroids to Δ4-steroids, a crucial step in steroidogenesis. In scientific research, 3beta-HSD inhibitors are essential tools for studying the regulation of steroid hormone production and its impact on various physiological processes such as metabolism, reproduction, and stress response. Researchers use these inhibitors to explore the enzyme's role in endocrine pathways, understand its involvement in metabolic and reproductive disorders, and investigate its broader implications in developmental biology. These inhibitors help to dissect the intricate networks of steroid metabolism and facilitate the study of how steroid hormone imbalances affect cellular function and organismal health. The availability of high-purity 3beta-HSD inhibitors from Santa Cruz Biotechnology ensures that experiments can be conducted with high precision and reproducibility, providing reliable data crucial for advancing scientific knowledge. By offering a comprehensive selection of these inhibitors, Santa Cruz Biotechnology supports the scientific community in developing new experimental models and uncovering novel insights into steroidogenesis and its regulation. View detailed information on our available 3beta-HSD Inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Epostane

80471-63-2sc-207627
1 mg
$372.00
1
(0)

Epostane functions as a potent 3beta-hydroxysteroid dehydrogenase (3beta-HSD) inhibitor, selectively modulating steroidogenesis pathways. Its unique structure allows for specific binding to the enzyme's active site, disrupting the conversion of Δ5-3β-hydroxysteroids to Δ4-ketosteroids. This inhibition alters reaction kinetics, leading to a buildup of precursor steroids. The compound's interactions with key residues in the enzyme enhance our understanding of steroid metabolism regulation and enzymatic specificity.

Trilostane

13647-35-3sc-208469
sc-208469A
10 mg
100 mg
$224.00
$1193.00
2
(1)

Trilostane acts as a selective inhibitor of 3beta-hydroxysteroid dehydrogenase (3beta-HSD), impacting steroid biosynthesis. Its molecular configuration enables it to effectively compete with natural substrates for the enzyme's active site, thereby hindering the transformation of Δ5-3β-hydroxysteroids. This competitive inhibition modifies the enzyme's kinetics, resulting in altered steroid profiles and providing insights into the intricate balance of steroid hormone regulation.