| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Epostane | 80471-63-2 | sc-207627 | 1 mg | $372.00 | 1 | |
Epostane functions as a potent 3beta-hydroxysteroid dehydrogenase (3beta-HSD) inhibitor, selectively modulating steroidogenesis pathways. Its unique structure allows for specific binding to the enzyme's active site, disrupting the conversion of Δ5-3β-hydroxysteroids to Δ4-ketosteroids. This inhibition alters reaction kinetics, leading to a buildup of precursor steroids. The compound's interactions with key residues in the enzyme enhance our understanding of steroid metabolism regulation and enzymatic specificity. | ||||||
Trilostane | 13647-35-3 | sc-208469 sc-208469A | 10 mg 100 mg | $224.00 $1193.00 | 2 | |
Trilostane acts as a selective inhibitor of 3beta-hydroxysteroid dehydrogenase (3beta-HSD), impacting steroid biosynthesis. Its molecular configuration enables it to effectively compete with natural substrates for the enzyme's active site, thereby hindering the transformation of Δ5-3β-hydroxysteroids. This competitive inhibition modifies the enzyme's kinetics, resulting in altered steroid profiles and providing insights into the intricate balance of steroid hormone regulation. | ||||||