Ziagen CAS: 136470-78-5
MF: C14H18N6O
MW: 286.34
A carbocyclic nucleoside analogue with inhibitory activity against HIV-1.

Ziagen (CAS 136470-78-5)

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备用名: Abacavir
应用; Ziagen is a carbocyclic nucleoside analogue with inhibitory activity against HIV-1
CAS号码: 136470-78-5
纯度: ≥98%
分子量: 286.34
分子式: C14H18N6O
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Ziagen is the brand name for abacavir sulfate, a synthetic carbocyclic nucleoside analogue with inhibitory activity against HIV-1. Abacavir is a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs work by blocking HIV reverse transcriptase (HIV-1 RT), an HIV enzyme.


参考文献

1. Daluge, S.M. et al. 1997. Antimicrob. Agents Chemother. 41(5): 1082-1093. PMID: 9145874

2. Foster, R.H. and Faulds, D. 1998. Drugs. 55(5): 729-36; discussion 737. PMID: 9585869

3. Staszewski, S. et al. 2001. JAMA. 285(9): 1155-1163. PMID: 11231744

4. Zucman, D. et al. 2007. J. Acquir. Immune Defic. Syndr. 45(1): 1-3. PMID: 17356469

物理状态 :
Solid
保存 :
Store at 4° C
熔点 :
80-85° C
沸点 :
636.0° C at 760 mmHg (Predicted)
密度 :
1.7 g/cm3 (Predicted)
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
SMILES :
C1CC1NC2=NC(=NC3=C2N=CN3C4CC(C=C4)CO)N

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