Thiazolyl Blue CAS: 298-93-1
MF: C18H16BrN5S
MW: 414.32

Thiazolyl Blue (CAS 298-93-1)

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备用名: Thiazolyl Blue is also known at MTT, MMT Tetrazolium, and Thiazolyl Blue Tetrazolium Bromide
应用; Thiazolyl Blue may be used in measurement of cell proliferation and is a membrane-permeable dye reduced by mitochondrial enzymes
CAS号码: 298-93-1
纯度: ≥98%
分子量: 414.32
分子式: C18H16BrN5S
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Thiazolyl Blue is a membrane-permeable yellow dye that is reduced by mitochondrial reductases in living cells to form the dark blue product, MTT Formazan (sc-215399). Spectrophotometric measurement of MTT Formazan at 540 or 570 nm allows quantitation of cell viability. Thiazolyl Blue is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. Thiazolyl Blue is also an electron acceptor used for studying NADP-dependent dehydrogenases.

物理状态 :
Solid
溶解度 :
Soluble in water (20 mg/ml), ethanol (20 mg/ml), 2-methoxyethanol (20 mg/ml), buffered salt solutions (5 mg/ml), culture media (5 mg/ml), and PBS (5 mg/ml).
保存 :
Store at 4° C
熔点 :
195° C (dec.)
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
RTECS :
XF8060000
PubChem CID :
MDL 号码 :
MFCD00011964
EC号码 :
206-069-5
Beilstein 注册 :
3825277
SMILES :
CC1=C(SC(=N1)[N+]2=NC(=NN2C3=CC=CC=C3)C4=CC=CC=C4)C.[Br-]

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PMID: # 30649537  Gorojod, RM.|Porte Alcon, S.|Dittler, ML.|Gonzalez, MC.|Kotler, ML.| et al. 2019. Toxicol. Sci. 169: 34-42.

PMID: # 30214567  Han, H. et al. 2018. Oncol Lett. 16: 4317-4324.

PMID: # 29862408  Fu, X.|Zhong, Z.|Hu, F.|Zhang, Y.|Li, C.|Yan, P.|Feng, L.|Shen, J.|Huang, B.| et al. 2018. Food Funct. 9: 3155-3165.

PMID: # 30316909  Alcon, SP. et al. 2018. Neuroscience.

PMID: # 28537657  Xia, HL.|Li, CJ.|Hou, XF.|Zhang, H.|Wu, ZH.|Wang, J.| et al. 2017. Eur Rev Med Pharmacol Sci. 21: 2244-2248.

PMID: # 27989859  Saneja, A.|Nayak, D.|Srinivas, M.|Kumar, A.|Khare, V.|Katoch, A.|Goswami, A.|Vishwakarma, RA.|Sawant, SD.|Gupta, PN.| et al. 2017. Eur J Pharm Sci. 97: 79-91.

PMID: # 26748999  Minaei, A. et al. 2016. Mol. Biol. Rep. 43: 99-105.

PMID: # 29345893  Ye, S.|Zhou, T.|Pan, D.|Lai, Y.|Yang, P.|Chen, M.|Wang, Y.|Hou, Z.|Ren, L.|Jiang, Y.| et al. 2016. J Biomed Nanotechnol. 12: 1820-33.

引用1 - 1034
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