Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Rabex-5 (Rab 5 GDP/GTP exchange factor), also known as RABGEF1, RAP1 or RABAPTIN-5-associated exchange factor for Rab 5, is a Rab guanine nucleotide exchange factor. Rabex-5 localizes to the cytoplasm and can associate with early endosomes. It consists of an N-terminal zinc finger domain, a GEF domain, an EET (early endosomal targeting) domain and a coiled-coil domain. The EET domain is important for the association of Rabex-5 with early endosomes and for the activation of Rab 5. Truncated Rabex-5 that is missing its EET domain can still function via an association with RABAPTIN-5. The Rabex-5/RABAPTIN-5 complex can target to early endosomes in a Rab 5-dependent manner through the binding of Rab5-GTP to RABAPTIN-5. In vitro, Rabex-5 exhibits GEF activity on its own, however, its association with RABAPTIN-5 increases its efficiency.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.