PtdIns-(4)-P1 (1,2-dihexanoyl) sodium salt MF: C21H38O16P2•2Na
MW: 654.44
A synthetic analog of natural phosphatidylinositol (PtdIns).

PtdIns-(4)-P1 (1,2-dihexanoyl) sodium salt

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备用名: Phosphatidylinositol-4-phosphate C-6; DHPI-4-P1
应用; PtdIns-(4)-P1 (1,2-dihexanoyl) sodium salt is a synthetic analog of natural phosphatidylinositol (PtdIns)
分子量: 654.44
分子式: C21H38O16P22Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

PtdIns-(4)-P1 (1,2-dihexanoyl) sodium salt is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. PtdIns-(4)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3) by phosphoinositol (PI)-specific kinases. Hydrolysis of PtdIns-(4,5)-P2 by PI-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.


参考文献

1. Exton, J.H. 1996. Annu. Rev. Pharmacol. Toxicol. 36: 481-509. PMID: 8725399
2. Majerus, P.W. 1992. Annu. Rev. Biochem. 61: 225-250. PMID: 1323235

外观 :
Lyophilized powder
物理状态 :
Solid
保存 :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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