PLAP CAS: 137314-60-4
MF: C106H184N28O30
MW: 2330.8
A phospholipase A2 activating peptide fragment consisting of 21 residues.

PLAP (CAS 137314-60-4)

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同义词: Phospholipase A2 activating peptide
应用; A phospholipase A2 activating peptide fragment consisting of 21 residues
CAS号码: 137314-60-4
纯度: ≥97%
分子量: 2330.8
分子式: C106H184N28O30
* 参考分析证明 大量特定数据 (包括水 含量).
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The phospholipase A2 activating protein (PLAP) is a 21-residue fragment that spans the PLAP-melittin homology sequence and is a member of the β-transducin (Gβ) superfamily. The peptide activates phospholipase A2 (10-fold at 1 μg/ml) in BC3H1 cell sonicates, as well as stimulates Golgi membrane tubulation and retrograde trafficking to the ER. Research indicates that PLAP peptide activates Ca(2+)-dependent phospholipase A(2) cPLA(2) in vascular smooth muscle cells, leading to arachidonic acid release and apoptosis.


参考文献

1. Peitsch, M.C., 1993. Trends Biochem. Sci. 18: 292-293. PMID: 8236442
2. Wang, H., et al. 1995. Gene. 161: 237-241. PMID: 7665086
3. Polizotto, R.S., et al. 1999. J. Cell. Biochem. 74: 670-683. PMID: 10440936
4. Pilane, C.M., et al. 2004. J. Cell. Physiol. 198: 48-52. PMID: 14584043

物理状态 :
Solid
顺序 :
H-Glu-Ser-Pro-Leu-Ile-Ala-Lys-Val-Leu-Thr-Thr-Glu-Pro-Pro-Ile- Ile-Thr-Pro-Val-Arg-Arg-OH
溶解度 :
Soluble in water.
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3

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