PKC ε inhibitor peptide MF: C37H65N9O13
MW: 844
Selectively and reversibly inhibits the translocation of Protein Kinase C epsilon.

PKC ε inhibitor peptide

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备用名: PKCε Translocation Inhibitor Peptide; EAVSLKPT; Protein Kinase Cε Translocation Inhibitor Peptide
应用; PKC ε inhibitor peptide is selectively and reversibly inhibits the translocation of Protein Kinase C epsilon
纯度: ≥97%
分子量: 844
分子式: C37H65N9O13
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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PKC ε inhibitor peptide is an octapeptide that selectively and reversibly inhibits the translocation of Protein Kinase C epsilon. Inhibition of PKCε translocation is relevant to the study of norepinephrine-mediated regulation of contraction in cardiomyocytes.


参考文献

1. Johnson, J A., et al., 1996. A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function. The Journal of biological chemistry. 271(40): 24962-6. PMID: 8798776
2. Yedovitzky, M., et al., 1997. Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells. The Journal of biological chemistry. 272(3): 1417-20. PMID: 8999804

外观 :
Lyophilized powder
物理状态 :
Solid
顺序 :
H-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
溶解度 :
Soluble in water.
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。

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引用1 - 1013

PMID: # 32781622  Jang, S.|Lee, S.|Park, H.| et al. 2020. Molecules. 25:

PMID: # 27330081  Sen, A. et al. 2016. The Journal of biological chemistry. 291: 16462-76.

PMID: # 25672459  Li, L. et al. 2015. Molecular medicine reports. 11: 4373-80.

PMID: # 24338688  2014. The Journal of biological chemistry. 289: 3148-63.

PMID: # 24806747  2014. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme. 46: 390-6.

PMID: # 25490397  2014. PloS one. 9: e113485.

PMID: # 20615477  2010. Prostaglandins & other lipid mediators. 93: 84-92.

PMID: # 20299424  2010. The Journal of pharmacology and experimental therapeutics. 333: 970-5.

PMID: # 19706599  Gayen, JR. et al. 2009. The Journal of biological chemistry. 284: 28498-509.

PMID: # 18039843  2008. Molecular and cellular biology. 28: 1007-17.

引用1 - 1013
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