Date published: 2025-9-9

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Mcl-1 抗体 (C-2): sc-377487

5.0(6)
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说明书
  • Mcl-1抗体(C-2)是小鼠单克隆IgM κ, 在8篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的Mcl-1的内部区域内的氨基酸111-149之间
  • 推荐用于 mouse, rat 和 human 来源的Mcl-1 long and short forms WB, IP, IF, IHC(P) 和 ELISA检测; 也和以下物种反应,包括: 和 equine and canine
  • 看 Mcl-1 (22): sc-12756,可查看有标记的 Mcl-1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成Mcl-1 抗体 (C-2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

B细胞慢性淋巴细胞白血病/淋巴瘤2(Bcl-2)能阻止细胞在接受各种刺激后发生死亡,并在生长因子撤除后赋予某些造血细胞系以抗死亡效应。髓系细胞白血病1(Mcl-1)与Bcl-2具有序列同源性,并且与Bcl-2进一步相似,因为它的表达促进了细胞活性。p53和Mcl-1通过介导Bcl-2拮抗剂杀手(Bak)活性对线粒体凋亡产生相反的作用。Mcl-1是早期造血祖细胞稳态所必需的重要且特异的调节因子。糖原合成酶激酶3(GSK3)控制Mcl-1的稳定性,这影响生长因子、PI 3激酶和AKT对细胞凋亡的调控。Mcl-1蛋白缺乏的小鼠显示B淋巴细胞和T淋巴细胞显著减少,这与在IL-7或IL-7R缺乏的小鼠中观察到的效果相似。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Mcl-1 抗体 (C-2)

sc-377487
200 µg/ml
$316.00

Mcl-1 (C-2) 中和勝肽

sc-377487 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-377487 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Wb实验效果很好我们从上海圣克鲁斯公司获得试用装。实验中,使用1:2000 应用于人胶质瘤细胞系U251等的wb分析。效果很好,值得推荐!
Date published: 2017-07-17
Rated 5 out of 5 by from Great antibody for Mcl-1Look no further, this one's great for IHC on paraffin section, IF and for Western blotting. Easy choice!
Date published: 2017-01-17
Rated 5 out of 5 by from Good publishable data in WB in rat A7r5 cellsGood publishable data in WB in rat A7r5 cells. -SCBT Publication Review
Date published: 2015-05-13
Rated 5 out of 5 by from Good specificity in WB in KGood specificity in WB in K-562, AML-193 and BJAB whole cell lysates. -SCBT QC
Date published: 2015-04-20
Rated 5 out of 5 by from Great immunoperoxidase nuclear staining inGreat immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human lymph node tissue. -SCBT QC
Date published: 2015-01-30
Rated 5 out of 5 by from Robust signal in WB in human transfectedRobust signal in WB in human transfected 293T whole cell lysates. -SCBT QC
Date published: 2015-01-04
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Mcl-1 抗体 (C-2) is rated 5.0 out of 5 by 6.
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