Kanamycin B sulfate CAS: 29701-07-3
MF: C18H37N5O10•H2SO4
MW: 581.59
Highly potent antibiotic against Gram-negative bacteria often used in cell culture.

Kanamycin B sulfate (CAS 29701-07-3)

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Kanamycin B sulfate is rated 5.0 out of 5 by 1.
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备用名: Bekanamycinsulfate salt
应用; Kanamycin B sulfate is highly potent antibiotic against Gram-negative bacteria often used in cell culture
CAS号码: 29701-07-3
纯度: ≥95%
分子量: 581.59
分子式: C18H37N5O10•H2SO4
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Kanamycin B is an aminoglycoside with antibiotic properties that associates with bacterial ribosomal RNA. The compound is highly potent against gram-negative bacteria. Other members of the aminoglycoside group include Kanamycin A (sc-205358) and Amikacin (sc-202457). Kanamycin B has five amino groups and has a stronger association with acidic phospholipids in comparison to Kanamycin A. Studies have shown that the Kcat value of the kanamycin group is higher compared to the neomycin group.


参考文献

1. Basak, K. and Majumdar, S.K. 1973. Antimicrob. Agents Chemother. 4: 6-10. PMID: 4791483
2. Yung, M.W. and Green, C. 1987. J. Antibiot. 40: 862-867. PMID: 3610836
3. Carrier, D., et al. 1997. Biochem. Pharmacol. 53: 401-408. PMID: 9065744
4. Kwon, M., et al. 2001. Mol. Cells. 11: 303-311. PMID: 11459219
5. Norris, A.L., et al. 2010. Biochemistry. 49: 4027-4035. PMID: 20387903

外观 :
Crystalline powder
物理状态 :
Solid
来源于 :
Streptomyces kanamyceticus
溶解度 :
Soluble in water (50 mg/ml), and aqueous solution (92.3 mg/ml).
保存 :
Store at -20° C
沸点 :
807.7° C at 760 mmHg (Predicted)
折射率 :
n20D 1.67 (Predicted)
IC50 :
Bacillus subtilis: IC50 = 0.39 ug.mL-1; Staphylococcus aureus: IC50 = 1.56 ug.mL-1; Mycobacterium tuberculosis: IC50 = 2.5 ug.mL-1; Escherichia coli: IC50 = 3.13 ug.mL-1; Pseudomonas aeruginosa: IC50 = 3.13 ug.mL-1
仅供科研使用。不可用于诊断或治疗。
RTECS :
WK1976500
PubChem CID :
默克索引 :
14: 5281
EC号码 :
225-170-5

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