Boeckler, F., et al., FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology 175, 7-17 , (2004) Loeber, S., et al., Rationally based efficacy tuning of selective dopamine D4 receptor ligands leading to the complete antagonist 2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213). J. Med. Chem. 44, 2691-2694 , (2001)
抑制剂:
D4DR.
物理状态 :
Solid
溶解度 :
Soluble in DMSO: ~24 mg/mL with warming up to 60° C: water: insoluble