Fasudil dihydrochloride (CAS 203911-27-7)

外观 :

Powder

物理状态 :

Solid

溶解度 :

Soluble in water (>10 mg/ml).

保存 :

Store at -20° C

熔点 :

248-249° C

折射率 :

n²⁰_D 1.62 (Predicted)

IC50 :

Rock: IC₅₀ = 180 nM (human); Rock-1: IC₅₀ = 300 nM (human); Rock-2: IC₅₀ = 400 nM (human); PRK2: IC₅₀ = 780 nM (human); PKN: IC₅₀ = 1.7 µM (human)

Ki 数据 :

Rock-1: K_i= 31.62 nM (human); LOC389906: K_i= 50.12 nM (human); Rock-2: K_i= 50.12 nM (human); PKAα cat: K_i= 79.43 nM (human); CLK4: K_i= 316.23 nM (human)

德国水公害等级 :

3

RTECS :

HM4031166

PubChem CID :

Merck 索引 :

14: 3942

MDL 号码 :

MFCD00153805

SMILES :

C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl