Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Diphtheria Toxoid Antibody (11D9) is a high quality monoclonal Diphtheria Toxoid antibody (also designated Diphtheria Toxoid antibody) suitable for the detection of the Diphtheria Toxoid protein of Corynebacterium diphtheriae origin. Diphtheria Toxoid Antibody (11D9) is available as the non-conjugated anti-Diphtheria Toxoid antibody. Diphtheria Toxoid is a 567 amino acid proenzyme that is produced by corynephage-β infection of Corynebacterium diphtheriae. Functioning as an enzymatic catalyst, Diphtheria Toxoid participates in the covalent attachment of elongation factor 2 (EF-2) to the ADP ribose moiety of NAD, thereby killing the infected cell. Diphtheria Toxoid works in three sequential steps, the first of which is penetration of the cell via receptor-mediated endocytosis. The toxin then translocates across the membrane into the cytoplasm where it ultimately attaches an ADP-ribosyl group to a modified histidine on EF-2, thus blocking protein synthesis and causing cell death. These steps are performed by three distinct structural domains: the receptor-binding domain (R), the pore-forming membrane-translocation domain (T) and the catalytic domain (C). Although only a single molecule of Diphtheria Toxoid is sufficient to kill a cell, toxicity can be repressed by DtxR, an iron-dependent transcriptional repressor that downregulates the expression of various virulence factors, including Diphtheria Toxoid.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.