Date published: 2025-9-6

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Dermcidin 抗体 (E-7): sc-393728

5.0(2)
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说明书
  • Dermcidin抗体(E-7)是小鼠单克隆IgG1 (kappa轻链),规格为200 µg/ml
  • 免疫原氨基酸序列20-110位于human物种的Dermcidin的C-terminus
  • 推荐用于 和 human 来源的Dermcidin precursor and DCD-1 active peptide WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRP是Dermcidin Antibody (E-7) for WB applications. 的首选辅助检测试剂,这些试剂现与Dermcidin Antibody (E-7) 打包提供(请参阅下面的订购信息)。

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    関連項目

    抗菌肽参与先天免疫反应,可能为抵抗感染提供保护屏障。Dermcidin基因编码一种抗菌肽DCD-1,该抗菌肽在汗腺中持续表达,分泌到汗液中,并运输到表皮表面。DCD-1对多种病原微生物表现出抗菌活性。乳腺癌中Dermcidin的过度表达促进细胞生长和存活,并伴随着其位于人类染色体12q13.2的位点发生局部拷贝数增加。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    Dermcidin 抗体 (E-7) 参考文献:

    1. 肝细胞中 Dermcidin 的表达无需 N-糖基化即可提高存活率,但需要天冬酰胺残基。  |  Lowrie, AG., et al. 2006. Br J Cancer. 94: 1663-71. PMID: 16685272
    2. 一系列原发性人类肿瘤和缺氧/氧化应激人类细胞系中皮肤苷的表达变化。  |  Stewart, GD., et al. 2008. Br J Cancer. 99: 126-32. PMID: 18594538
    3. 金黄色葡萄球菌突变体筛选揭示了人类抗菌肽 dermcidin 与膜磷脂的相互作用。  |  Li, M., et al. 2009. Antimicrob Agents Chemother. 53: 4200-10. PMID: 19596877
    4. Vitronectin和dermcidin血清水平可预测AJCC I-II早期黑色素瘤的转移进展。  |  Ortega-Martínez, I., et al. 2016. Int J Cancer. 139: 1598-607. PMID: 27216146
    5. 人体鼻窦分泌物中真皮素的表达。  |  Cottrill, EE., et al. 2017. Int Forum Allergy Rhinol. 7: 154-159. PMID: 27650261
    6. Dermcidin、Salusin-α、Salusin-β和 TNF-α 在人类布鲁氏菌病发病机制中的作用。  |  Sağmak Tartar, A., et al. 2019. Iran J Immunol. 16: 182-189. PMID: 31182692
    7. 细胞表面的 GRP78 和 Dermcidin 通过 Wnt 信号合作调节乳腺癌细胞的迁移。  |  Lager, TW., et al. 2021. Oncogene. 40: 4050-4059. PMID: 33981001
    8. 人皮素能保护小鼠免受肝脏缺血再灌注引起的局部和远端炎症损伤的影响  |  Qiang, X., et al. 2021. Front Immunol. 12: 821154. PMID: 35095926
    9. Dermcidin 衍生多肽:DCD(86-103)通过 ST2 激活肥大细胞诱发皮肤炎症反应。  |  Che, D., et al. 2022. Immunol Lett. 251-252: 29-37. PMID: 36191776
    10. 局部使用 Sandalore® 可增加器官培养的人体皮肤表皮真皮素的合成。  |  Edelkamp, J., et al. 2023. Skin Pharmacol Physiol. 36: 117-124. PMID: 36702115

    订购信息

    产品名称产品编号规格价格数量收藏夹

    Dermcidin 抗体 (E-7)

    sc-393728
    200 µg/ml
    $316.00

    Dermcidin (E-7): m-IgG Fc BP-HRP 套装

    sc-540906
    200 µg Ab; 10 µg BP
    $354.00

    Dermcidin (E-7): m-IgG1 BP-HRP 套装

    sc-542456
    200 µg Ab; 20 µg BP
    $354.00

    What is the recommended starting dilution for Western blot for sc-393728: Dermcidin (E-7) monoclonal antibody?

    Asked by: jenniferc
    The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
    Answered by: Technical Support
    Date published: 2017-03-22
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    Rated 5 out of 5 by from Good antibodyThe Dermcidin Antibody (E-7): sc-393728 works very well for Western blot applications, showing clear band with minimal background.
    Date published: 2017-01-18
    Rated 5 out of 5 by from Very good Western blot data of DermcidinVery good Western blot data of Dermcidin expression in non-transfected and human Dermcidin transfected CMV whole cell lysates. -SCBT QC
    Date published: 2013-06-15
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    Dermcidin 抗体 (E-7) is rated 5.0 out of 5 by 2.
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