Benfluorene MF: C20H15NO4
MW: 333.34
A selective inhibitor of CDK1 (IC50=28.8µM).

Benfluorene

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 96ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
应用; Benfluorene is a selective inhibitor of cdc2 (CDK1) (IC50=28.8μM)
分子量: 333.34
分子式: C20H15NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits
loading

Benfluorene is a selective inhibitor of CDK1 (IC50 = 28.8 μM) and has P-glycoprotein-modulating properties (inhibitory activity ratio 9.5 at 7 μM). It weakly inhibits CDK5 (6% inhibition at 10 μM) with no effect on CDK2 and CDK4 (IC50 > 100 μM).


参考文献

K. Brachwitz, et al.; J. Med. Chem. 46, 876 (2003).

外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble in DMSO or 100% ethanol. Insoluble in water.
保存 :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
CCOC(=O)C1=CN=C2C(=C1C3=CC=CC=C3)C4=C(O2)C=CC(=C4)O

下载SDS

分析证明书

在PDF文件上阅读,打印和批注,Adobe阅读器是必须的

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 91ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 7ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;