1,2-Dipalmitoyl-L-alpha-phosphatidyl-D-myo-inositol 4,5-bisphosphate CAS: 120595-88-2
MF: C41H81O19P3
MW: 971.0
A critical component in signaling pathways.

1,2-Dipalmitoyl-L-α-phosphatidyl-D-myo-inositol 4,5-bisphosphate (CAS 120595-88-2)

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应用; 1,2-Dipalmitoyl-L-alpha-phosphatidyl-D-myo-inositol 4,5-bisphosphate is a critical component in signaling pathways
CAS号码: 120595-88-2
纯度: ≥98%
分子量: 971.0
分子式: C41H81O19P3
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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1,2-Dipalmitoyl-L-α-phosphatidyl-D-myo-inositol 4,5-bisphosphate is a 4,5-bisphosphate group on the inositol ring is critical for binding specifically to PH domains that are commonly present in signalling proteins. Also found in cytoskeleton.


参考文献

Structure of the binding site for inositol phosphate in a PH domain: M. Hyvonen, et al.; EMBO J. 14, 4676 (1995) Abstract Inositolpolyphosphates and their binding proteins--a short review: B. Huisamen & A. Lochner; Mol. Cell. Biochem. 157, 229 (1996) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate: T.F. Franke, et al.; Science 275, 665 (1997) Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking: T.F. Martin; Annu. Rev. Cell. Dev. Biol. 14, 231 (1998), (Review) The synthesis and cellular roles of phosphatidylinositol 4,5- bisphosphate: A. Toker; Curr. Opin. Cell Biol. 10, 254 (1998) Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5- bisphosphate: R. Rohatgi, et al.; J. Cell Biol. 150, 1299 (2000)

外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble in water, DMSO, methanol, ethanol, and chloroform.
保存 :
Store at -20° C
沸点 :
995.95° C at 760 mmHg (Predicted)
密度 :
1.27 g/cm3 (Predicted)
折射率 :
n20D 1.52 (Predicted)
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
MDL 号码 :
MFCD01861927
SMILES :
CCCCCCCCCCCCCCCC(=O)OC[[email protected]](COP(=O)(O)O[[email protected]@H]1[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]]1O)OP(=O)(O)O)OP(=O)(O)O)O)O)OC(=O)CCCCCCCCCCCCCCC

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PMID: # 28697598  Zheng, K. et al. 2017. J. Agric. Food Chem. 65: 6625-6637.

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