Z-WEHD-FMK MF: C37H42FN7O10
MW: 763.78
An inhibitor of caspase-1, caspase-4, caspase-5 and caspase-8.

Z-WEHD-FMK

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Alternativa namn: Benzyloxycarbonyl-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Ansökan Z-WEHD-FMK is an inhibitor of caspase-1, caspase-4, caspase-5 and caspase-8
Molekylvikt: 763.78
Molekylär formel: C37H42FN7O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible inhibitor of caspase-5. It also inhibits caspase-1, caspase-4 and caspase-8. Caspase inhibitors play an important role in investigating biological processes. The caspase family of proteins function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Following use of the inhibitor, standard apoptosis assays can then be used to examine treated cells for evidence of apoptosis.
For the fluorometric determination of caspase-6 activity, the following caspase apoptosis detection kit is available from Santa Cruz: Caspase-6 Kit (sc-4266 AK).

Physical State :
Solid
Sequence :
Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK
LAGRING :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
SMILES :
COC(=O)CC[[email protected]@H](C(=O)N[[email protected]@H](CC1=CN=CN1)C(=O)N[[email protected]@H](CC(=O)OC)C(=O)CF)NC(=O)[[email protected]](CC2=CNC3=CC=CC=C32)NC(=O)OCC4=CC=CC=C4

Download SDS (MSDS)

Certificate of Analysis

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Z-WEHD-FMK  Produkt Citat

See how others have used Z-WEHD-FMK. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 31035052  Huang, WC.|Gu, PY.|Fang, LW.|Huang, YL.|Lin, CF.|Liou, CJ.| et al. 2019. Phytomedicine. 61: 152852.

Citations 1 to 1 of 1 total
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