Trinactin CAS: 7561-71-9
MF: C43H70O12
MW: 779.0
A hydrophobic cyclic ester that acts as a macrotetrolide antibiotic.

Trinactin (CAS 7561-71-9)

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Ansökan Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic
CAS Nr: 7561-71-9
Renhet: >95%
Molekylvikt: 779.0
Molekylär formel: C43H70O12
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Trinactin is a hydrophobic cyclic ester that acts as a macrotetrolide antibiotic, isolated from Streptomyces aureus. Steady-state ion transport studies demonstrate that Trinactin behaves as an univalent cation cyclicly carrier. Trinactin has been shown to block incorporation of 3H-thymidine into lymphocytes treated with Concanavalin A (sc-203007) and is a homolog of Nonactin (sc-203164). Additionally, metabolic studies show that Trinactin has induced damped oscillatory mitochondrial swelling.


Konferenser

1. Meyers, E., et al. 1965. J. Antibiot. 18: 128-129. PMID: 14336167
2. Hladky, S.B. 1975. Biochim. Biophys. Acta. 375: 350-362. PMID: 1173049
3. Hertz, M.M., et al. 1977. Acta Physiol. Scand. 101: 501-503. PMID: 596227
4. Laprade, R., et al. 1984. Can. J. Biochem. Cell Biol. 62: 738-751. PMID: 6498590
5. Tanouchi, Y., et al. 1987. Jpn. J. Ophthalmol. 31: 218-229. PMID: 3499534

Appearance :
Film
Physical State :
Solid
Derived From :
Streptomyces sp.
Solubility :
Soluble in ethyl acetate, DMSO, 100% ethanol (moderately ), and methanol (moderately ).
LAGRING :
Store at -20° C
Boiling Point :
909.68° C at 760 mmHg (Predicted)
Density :
1.02 g/cm3 (Predicted)
Refractive Index :
n20D 1.45 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00950778

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Certificate of Analysis

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