Anti-TLE5 Antibody (C-7) is a mouse monoclonal IgG2b (kappa light chain) TLE5 antibody provided at 200 µg/ml
raised against amino acids 127-197 mapping at the C-terminus of TLE5 of human origin
Anti-TLE5 Antibody (C-7) is recommended for detection of TLE5 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-TLE5 Antibody (C-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TLE5 (C-7): sc-515756.
m-IgGκ BP-HRP is the preferred secondary detection reagent for TLE5 Antibody (C-7) for WB applications. This reagent is now offered in a bundle with TLE5 Antibody (C-7) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TLE5 Antibody (C-7) is a high quality monoclonal TLE5 antibody (also designated Gp130-associated protein GAM antibody or Groucho-related protein 5 antibody) suitable for the detection of the TLE5 protein of mouse, rat and human origin. TLE5 Antibody (C-7) is available as both the non-conjugated anti-TLE5 antibody form, as well as multiple conjugated forms of anti-TLE5 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Notch signaling pathway controls cellular interactions important for the specification of a variety of fates in both vertebrates and invertebrates. Key players in the Notch pathway are the TLE genes (for transducin-like enhancer of split, also designated ESG for enhancer of split groucho), which are human homologs of the Drosophila groucho gene. TLE5, also known as AES (amino-terminal enhancer of split), GRG or ESP1, is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFκB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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