Anti-TIP30 Antibody (F-10) is a mouse monoclonal IgG1 (kappa light chain) TIP30 antibody provided at 200 µg/ml
raised against amino acids 145-217 mapping near the C-terminus of TIP30 of human origin
Anti-TIP30 Antibody (F-10) is recommended for detection of TIP30 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-TIP30 Antibody (F-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TIP30 (F-10): sc-515728.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TIP30 Antibody (F-10) is a high quality monoclonal TIP30 antibody (also designated TIP30 antibody) suitable for the detection of the TIP30 protein of mouse, rat and human origin. TIP30 Antibody (F-10) is available as both the non-conjugated anti-TIP30 antibody form, as well as multiple conjugated forms of anti-TIP30 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. TIP30 (30 kDa HIV-1 TAT-interacting protein), also known as HTATIP2 (HIV-1 TAT-interactive protein 2) or CC3, is a ubiquitously expressed protein that functions as an oxidoreductase. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induction of apoptosis. TIP30 interacts with the ERα-interacting coactivator NCoA-5 and functions to regulate liganded and unliganded ERα-mediated c-Myc transcription. More specifically, when overexpressed TIP30 represses c-Myc transcription mediated by ERα, while the deficiency of TIP30 leads to an increase in c-Myc transcription. In addition, TIP30 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in TIP30 are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for TIP30 in antitumor therapy.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences