Anti-TCR C β 1 Antibody (JOVI.1) is a mouse monoclonal IgG2a κ TCR C β 1 antibody, cited in 1 publications, provided at 200 µg/ml
raised against thymus, spleen and mesenteric lymph nodes isolated from a mouse transgenic for human Vb3 TcR
TCR C beta 1 Antibody (JOVI.1) is recommended for detection of TCR C β 1 of human origin by IP, IF and FCM
TCR C beta 1 Antibody (JOVI.1) is available conjugated to agarose for IP; to HRP for WB, IHC(P) and ELISA; and to FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TCR C β 1 (JOVI.1): sc-53196.
m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for TCR C β 1 Antibody (JOVI.1) for WB and IHC(P) applications. These reagents are now offered in bundles with TCR C β 1 Antibody (JOVI.1) (see ordering information below).
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Labware ships FedEx Ground free of charge to the contiguous US
TCR C β 1 Antibody (JOVI.1) is a high quality monoclonal TCR C beta 1 antibody (also designated TCR C β 1 antibody) suitable for the detection of the TCR C beta 1 protein of human origin. TCR C β 1 Antibody (JOVI.1) is available as both the non-conjugated anti-TCR C beta 1 antibody form, as well as multiple conjugated forms of anti-TCR C beta 1 antibody, including agarose, HRP, FITC and multiple Alexa Fluor® conjugates. The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. TCR is a heterodimer composed of either α and β or γ and δ chains. The vast majority of circulating T cells (95%) express the α/β heterodimer while roughly 2-5% express the γ/δ heterodimer. Recognizing such a variety of antigens requires diverse specificities in the TCR repertoire. This is obtained by the somatic recombination of variable (V), diversity (D), joining (J), and constant (C) gene segments in the assembly of each TCR chain. The TCR β and γ chain genes lie in distinct loci, while the genes encoding the TCR α and δ chains comprise a single locus. During T cell development, the β chain is synthesized by first joining a D segment with a J segment, then adding a V segment with the D-J gene. The C segment is later joined by splicing at the RNA level. Genetic mutations involving the T cell receptor β locus have been associated with T cell lymphomas.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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To place an order using RMB or to ship to mainland China, please visit www.scbio.cn